Tissue expression of SBSN - Summary - The Human Protein Atlas

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SBSN

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TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	SBSN
Gene description	Suprabasin
Protein class	Plasma proteins Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (esophagus, skin)
GTEx:	Tissue enhanced (esophagus, skin)
FANTOM5:	Group enriched (cervix, uterine, esophagus, tonsil)

Protein evidence

Evidence at protein level

Protein expression

Selective membranous expression in squamous epithelia.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA062568 , HPA067734
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (esophagus, skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (esophagus, skin)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (cervix, uterine, esophagus, tonsil)

GENE INFORMATION
Gene name	SBSN (HGNC Symbol)
Synonyms	HLAR698, UNQ698
Description	Suprabasin (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	q13.12
Chromosome location (bp)	35523367 - 35528351
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000189001 (version 83.38)
Entrez gene	374897
UniProt	Q6UWP8 (UniProt - Evidence at protein level)
neXtProt	NX_Q6UWP8
Antibodypedia	SBSN antibodies

PROTEIN BROWSER

SBSN-001	SBSN-002	SBSN-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SBSN-001 ENSP00000428771 ENST00000518157	Q6UWP8 [Direct mapping] Suprabasin Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0008150 [biological_process] GO:0070062 [extracellular exosome] Show all	247 aa 25.3 kDa	Yes	0
SBSN-002 ENSP00000430242 ENST00000452271	Q6UWP8 [Direct mapping] Suprabasin Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003674 [molecular_function] GO:0005737 [cytoplasm] GO:0008150 [biological_process] GO:0070062 [extracellular exosome] Show all	590 aa 60.5 kDa	Yes	0
SBSN-003 ENSP00000468646 ENST00000588674	K7ESC4 [Direct mapping] Suprabasin Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		149 aa 15.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.