Cell atlas - ASMT - The Human Protein Atlas

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ASMT

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	ASMT
Gene description	Acetylserotonin O-methyltransferase
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	ASMT (HGNC Symbol)
Synonyms	ASMTY, HIOMT, HIOMTY
Description	Acetylserotonin O-methyltransferase (HGNC Symbol)
Entrez gene summary	This gene belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2010]
Chromosome	X
Cytoband	p22.33
Chromosome location (bp)	1615001 - 1643081
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000196433 (version 83.38)
Entrez gene	438
UniProt	P46597 (UniProt - Evidence at protein level)
neXtProt	NX_P46597
Antibodypedia	ASMT antibodies

PROTEIN BROWSER

ASMT-001	ASMT-002	ASMT-003	ASMT-004

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ASMT-001 ENSP00000370639 ENST00000381241	P46597 [Direct mapping] Acetylserotonin O-methyltransferase A0A024RBT9 [Target identity:100%; Query identity:100%] HCG1981394, isoform CRA_b Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0005829 [cytosol] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0008757 [S-adenosylmethionine-dependent methyltransferase activity] GO:0017096 [acetylserotonin O-methyltransferase activity] GO:0030187 [melatonin biosynthetic process] GO:0032259 [methylation] GO:0034641 [cellular nitrogen compound metabolic process] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0044281 [small molecule metabolic process] GO:0046219 [indolalkylamine biosynthetic process] Show all	373 aa 41.7 kDa	No	0
ASMT-002 ENSP00000370627 ENST00000381229	P46597 [Direct mapping] Acetylserotonin O-methyltransferase X5D2A4 [Target identity:100%; Query identity:100%] Acetylserotonin O-methyltransferase isoform B Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0005829 [cytosol] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0017096 [acetylserotonin O-methyltransferase activity] GO:0030187 [melatonin biosynthetic process] GO:0032259 [methylation] GO:0034641 [cellular nitrogen compound metabolic process] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0044281 [small molecule metabolic process] GO:0046219 [indolalkylamine biosynthetic process] Show all	345 aa 38.5 kDa	No	0
ASMT-003 ENSP00000370631 ENST00000381233	P46597 [Direct mapping] Acetylserotonin O-methyltransferase X5D784 [Target identity:100%; Query identity:100%] Acetylserotonin O-methyltransferase isoform C Show all	Enzymes ENZYME proteins Transferases Predicted intracellular proteins Show all	GO:0005829 [cytosol] GO:0006412 [translation] GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0017096 [acetylserotonin O-methyltransferase activity] GO:0030187 [melatonin biosynthetic process] GO:0032259 [methylation] GO:0034641 [cellular nitrogen compound metabolic process] GO:0042802 [identical protein binding] GO:0042803 [protein homodimerization activity] GO:0044281 [small molecule metabolic process] GO:0046219 [indolalkylamine biosynthetic process] Show all	298 aa 33.2 kDa	No	0
ASMT-004 ENSP00000392053 ENST00000432523	I7HFW6 [Direct mapping] Acetylserotonin O-methyltransferase Show all	Predicted intracellular proteins Show all	GO:0008168 [methyltransferase activity] GO:0008171 [O-methyltransferase activity] GO:0032259 [methylation] Show all	124 aa 14 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.