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ZSCAN16

GENERAL INFORMATION

Gene name

 ZSCAN16

Gene description

 Zinc finger and SCAN domain containing 16

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Mixed
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nuclear expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA007290
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PROGNOSTIC SUMMARY
Prognostic marker in ovarian cancer (favourable), urothelial cancer (favourable), lung cancer (favourable) and cervical cancer (favourable).
Ovarian cancer p<0.001
Urothelial cancer p<0.001
Lung cancer p<0.001
Cervical cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA007290

GENE INFORMATION

Gene name

 ZSCAN16 (HGNC Symbol)

Synonyms

 dJ265C24.3, FLJ22191, ZNF392, ZNF435

Description

 Zinc finger and SCAN domain containing 16 (HGNC Symbol)

Entrez gene summary

Chromosome

 6

Cytoband

 p22.1

Chromosome location (bp)

 28124560 - 28130082

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000196812 (version 83.38)

Entrez gene

 80345

UniProt

 Q9H4T2 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9H4T2

Antibodypedia

 ZSCAN16 antibodies

PROTEIN BROWSER
ZSCAN16-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZSCAN16-001
ENSP00000366527
ENST00000340487
Q9H4T2 [Direct mapping]
Zinc finger and SCAN domain-containing protein 16
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Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0043565 [sequence-specific DNA binding]
GO:0046872 [metal ion binding]
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 348 aa
40.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.