Cell atlas - DTHD1 - The Human Protein Atlas

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DTHD1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	DTHD1
Gene description	Death domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Not detected
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Not detected Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	DTHD1 (HGNC Symbol)
Synonyms	FLJ16686
Description	Death domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains a death domain. Death domain-containing proteins function in signaling pathways and formation of signaling complexes, as well as the apoptosis pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Chromosome	4
Cytoband	p14
Chromosome location (bp)	36281622 - 36345756
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197057 (version 83.38)
Entrez gene	401124
UniProt	Q6ZMT9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZMT9
Antibodypedia	DTHD1 antibodies

PROTEIN BROWSER

DTHD1-001	DTHD1-002	DTHD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DTHD1-001 ENSP00000350103 ENST00000357504	Q6ZMT9 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	616 aa 69.8 kDa	No	0
DTHD1-002 ENSP00000424426 ENST00000507598	D6RB49 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	821 aa 92.8 kDa	No	0
DTHD1-201 ENSP00000401597 ENST00000456874	Q6ZMT9 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	781 aa 88.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.