Tissue expression of DTHD1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	DTHD1
Gene description	Death domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (fallopian tube)
GTEx:	Tissue enhanced (fallopian tube)
FANTOM5:	Tissue enhanced (lung)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (fallopian tube)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (fallopian tube)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (lung)

GENE INFORMATION
Gene name	DTHD1 (HGNC Symbol)
Synonyms	FLJ16686
Description	Death domain containing 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which contains a death domain. Death domain-containing proteins function in signaling pathways and formation of signaling complexes, as well as the apoptosis pathway. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Chromosome	4
Cytoband	p14
Chromosome location (bp)	36281622 - 36345756
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000197057 (version 83.38)
Entrez gene	401124
UniProt	Q6ZMT9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6ZMT9
Antibodypedia	DTHD1 antibodies

PROTEIN BROWSER

DTHD1-001	DTHD1-002	DTHD1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DTHD1-001 ENSP00000350103 ENST00000357504	Q6ZMT9 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	616 aa 69.8 kDa	No	0
DTHD1-002 ENSP00000424426 ENST00000507598	D6RB49 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	821 aa 92.8 kDa	No	0
DTHD1-201 ENSP00000401597 ENST00000456874	Q6ZMT9 [Direct mapping] Death domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005737 [cytoplasm] GO:0007165 [signal transduction] GO:0008540 [proteasome regulatory particle, base subcomplex] GO:0032436 [positive regulation of proteasomal ubiquitin-dependent protein catabolic process] GO:0070682 [proteasome regulatory particle assembly] Show all	781 aa 88.3 kDa	No	0