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ZNF81

GENERAL INFORMATION

Gene name

 ZNF81

Gene description

 Zinc finger protein 81

Protein class

 Disease related genes
Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Mixed
GTEx:Mixed
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General cytoplasmic expression with a granular pattern.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
HPA001689
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 ZNF81 (HGNC Symbol)

Synonyms

 HFZ20, MRX45

Description

 Zinc finger protein 81 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein that likely functions as a transcription factor. The protein contains an N-terminal KRAB domain and several C2H2-type zinc finger motifs. Mutations in this gene cause mental retardation X-linked type 45 (MRX45). [provided by RefSeq, May 2010]

Chromosome

 X

Cytoband

 p11.23

Chromosome location (bp)

 47836902 - 48002561

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197779 (version 83.38)

Entrez gene

 347344

UniProt

 P51508 (UniProt - Evidence at protein level)

neXtProt

 NX_P51508

Antibodypedia

 ZNF81 antibodies

PROTEIN BROWSER
ZNF81-001
ZNF81-002
ZNF81-003
ZNF81-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ZNF81-001
ENSP00000366153
ENST00000376954
P51508 [Direct mapping]
Zinc finger protein 81
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Disease related genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 661 aa
76 kDa 		No 0
ZNF81-002
ENSP00000334641
ENST00000334937
B1AJV1 [Direct mapping]
Zinc finger protein 81
Show all
Predicted intracellular proteins
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 69 aa
7.9 kDa 		No 0
ZNF81-003
ENSP00000366149
ENST00000376950
B1AJV2 [Direct mapping]
Zinc finger protein 81
Show all
Predicted intracellular proteins
Show all
GO:0003676 [nucleic acid binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0006355 [regulation of transcription, DNA-templated]
Show all
 103 aa
11.5 kDa 		No 0
ZNF81-201
ENSP00000341151
ENST00000338637
P51508 [Direct mapping]
Zinc finger protein 81
Show all
Predicted intracellular proteins
Transcription factors
   Zinc-coordinating DNA-binding domains
Disease related genes
Show all
GO:0003676 [nucleic acid binding]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0006351 [transcription, DNA-templated]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0046872 [metal ion binding]
Show all
 661 aa
76 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.