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AKAP17A

GENERAL INFORMATION

Gene name

 AKAP17A

Gene description

 A kinase (PRKA) anchor protein 17A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Mixed

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA043247
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed

GENE INFORMATION

Gene name

 AKAP17A (HGNC Symbol)

Synonyms

 721P, CCDC133, CXYorf3, DXYS155E, MGC39904, SFRS17A, XE7, XE7Y

Description

 A kinase (PRKA) anchor protein 17A (HGNC Symbol)

Entrez gene summary

 This locus encodes a protein kinase A anchoring protein. The encoded protein is part of the spliceosome complex and is involved in the regulation of alternate splicing in some mRNA precursors. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Sep 2010]

Chromosome

 X

Cytoband

 p22.33

Chromosome location (bp)

 1591593 - 1602514

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000197976 (version 83.38)

Entrez gene

 8227

UniProt

 Q02040 (UniProt - Evidence at protein level)

neXtProt

 NX_Q02040

Antibodypedia

 AKAP17A antibodies

PROTEIN BROWSER
AKAP17A-002
AKAP17A-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AKAP17A-002
ENSP00000370660
ENST00000381261
X6RAJ1 [Direct mapping]
A-kinase anchor protein 17A; HCG1981394, isoform CRA_d
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000166 [nucleotide binding]
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 446 aa
51.5 kDa 		No 0
AKAP17A-003
ENSP00000324827
ENST00000313871
Q02040 [Direct mapping]
A-kinase anchor protein 17A
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000166 [nucleotide binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005681 [spliceosomal complex]
GO:0005737 [cytoplasm]
GO:0006355 [regulation of transcription, DNA-templated]
GO:0006397 [mRNA processing]
GO:0007165 [signal transduction]
GO:0008380 [RNA splicing]
GO:0016607 [nuclear speck]
GO:0042113 [B cell activation]
GO:0043484 [regulation of RNA splicing]
GO:0044822 [poly(A) RNA binding]
GO:0051018 [protein kinase A binding]
Show all
 695 aa
80.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.