Cell atlas - MB - The Human Protein Atlas

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MB

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	MB
Gene description	Myoglobin
Protein class	Candidate cardiovascular disease genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SK-BR-3, T-47d)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SK-BR-3, T-47d) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	MB (HGNC Symbol)
Synonyms	PVALB
Description	Myoglobin (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Chromosome	22
Cytoband	q12.3
Chromosome location (bp)	35606764 - 35637951
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198125 (version 83.38)
Entrez gene	4151
UniProt	P02144 (UniProt - Evidence at protein level)
neXtProt	NX_P02144
Antibodypedia	MB antibodies

PROTEIN BROWSER

MB-001	MB-002	MB-003	MB-004	MB-005	MB-006	MB-007	MB-008	MB-201	MB-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MB-001 ENSP00000380489 ENST00000397326	P02144 [Direct mapping] Myoglobin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Candidate cardiovascular disease genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001666 [response to hypoxia] GO:0005344 [oxygen transporter activity] GO:0007507 [heart development] GO:0009725 [response to hormone] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0031444 [slow-twitch skeletal muscle fiber contraction] GO:0042542 [response to hydrogen peroxide] GO:0043353 [enucleate erythrocyte differentiation] GO:0046872 [metal ion binding] GO:0050873 [brown fat cell differentiation] GO:0070062 [extracellular exosome] Show all	154 aa 17.2 kDa	No	0
MB-002 ENSP00000386060 ENST00000401702	Q8WVH6 [Direct mapping] Myoglobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	99 aa 10.9 kDa	No	0
MB-003 ENSP00000403351 ENST00000443033	B0QYF8 [Direct mapping] Myoglobin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	143 aa 16 kDa	No	0
MB-004 ENSP00000384239 ENST00000406324	P02144 [Direct mapping] Myoglobin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Candidate cardiovascular disease genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	154 aa 17.2 kDa	No	0
MB-005 ENSP00000414243 ENST00000419229	F2Z337 [Direct mapping] Myoglobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	77 aa 8.6 kDa	No	0
MB-006 ENSP00000413309 ENST00000442617	B0QYF7 [Direct mapping] Myoglobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	74 aa 8.1 kDa	No	0
MB-007 ENSP00000397944 ENST00000451685	F2Z2F1 [Direct mapping] Myoglobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	106 aa 11.9 kDa	No	0
MB-008 ENSP00000389263 ENST00000447607	F2Z2F1 [Direct mapping] Myoglobin Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0015671 [oxygen transport] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] Show all	106 aa 11.9 kDa	No	0
MB-201 ENSP00000352835 ENST00000359787	P02144 [Direct mapping] Myoglobin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Candidate cardiovascular disease genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	154 aa 17.2 kDa	No	0
MB-202 ENSP00000380491 ENST00000397328	P02144 [Direct mapping] Myoglobin Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Plasma proteins Candidate cardiovascular disease genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005344 [oxygen transporter activity] GO:0019825 [oxygen binding] GO:0020037 [heme binding] GO:0046872 [metal ion binding] GO:0070062 [extracellular exosome] Show all	154 aa 17.2 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.