Cell atlas - EPS8L3 - The Human Protein Atlas

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EPS8L3

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Vesicles

Human cell
	Vesicles

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GENERAL INFORMATION
Gene name	EPS8L3
Gene description	EPS8-like 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to vesicles.
RNA cell category	Group enriched (Hep G2, CAPAN-2, CACO-2, EFO-21)
Protein evidence	Evidence at protein level
Main location	Localized to the Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA030998
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (Hep G2, CAPAN-2, CACO-2, EFO-21) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to vesicles.

Main location

Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA030998	Hep G2	Vesicles
	HPA030998	U-2 OS	Vesicles

GENE INFORMATION
Gene name	EPS8L3 (HGNC Symbol)
Synonyms	FLJ21522, MGC16817
Description	EPS8-like 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	109750080 - 109764027
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198758 (version 83.38)
Entrez gene	79574
UniProt	Q8TE67 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TE67
Antibodypedia	EPS8L3 antibodies

PROTEIN BROWSER

EPS8L3-001	EPS8L3-002	EPS8L3-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EPS8L3-001 ENSP00000358820 ENST00000369805	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	594 aa 66.9 kDa	No	0
EPS8L3-002 ENSP00000355255 ENST00000361965	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	593 aa 66.9 kDa	No	0
EPS8L3-003 ENSP00000354551 ENST00000361852	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	563 aa 63.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.