Tissue expression of EPS8L3 - Summary - The Human Protein Atlas

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EPS8L3

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	EPS8L3
Gene description	EPS8-like 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (colon, duodenum, gallbladder, rectum, small intestine, stomach)
GTEx:	Tissue enhanced (colon, small intestine)
FANTOM5:	Group enriched (colon, gallbladder, small intestine)

Protein evidence

Evidence at protein level

Protein expression

Membranous expression in the intestinal tract and gall bladder.

DATA RELIABILITY
Data reliability description	Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Approved based on 1 antibody. HPA030998
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, duodenum, gallbladder, rectum, small intestine, stomach)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (colon, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, gallbladder, small intestine)

GENE INFORMATION
Gene name	EPS8L3 (HGNC Symbol)
Synonyms	FLJ21522, MGC16817
Description	EPS8-like 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist. [provided by RefSeq, Jul 2008]
Chromosome	1
Cytoband	p13.3
Chromosome location (bp)	109750080 - 109764027
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198758 (version 83.38)
Entrez gene	79574
UniProt	Q8TE67 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TE67
Antibodypedia	EPS8L3 antibodies

PROTEIN BROWSER

EPS8L3-001	EPS8L3-002	EPS8L3-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
EPS8L3-001 ENSP00000358820 ENST00000369805	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	594 aa 66.9 kDa	No	0
EPS8L3-002 ENSP00000355255 ENST00000361965	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	593 aa 66.9 kDa	No	0
EPS8L3-003 ENSP00000354551 ENST00000361852	Q8TE67 [Direct mapping] Epidermal growth factor receptor kinase substrate 8-like protein 3 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] Show all	563 aa 63.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.