Fields »
ABOUT
HELP
BLOG
SYCP1

GENERAL INFORMATION

Gene name

 SYCP1

Gene description

 Synaptonemal complex protein 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (THP-1)
HPA (normal tissue):Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Nucleolar expression in seminiferous ducts.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA021083
SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA021083

GENE INFORMATION

Gene name

 SYCP1 (HGNC Symbol)

Synonyms

 CT8, HOM-TES-14, SCP1

Description

 Synaptonemal complex protein 1 (HGNC Symbol)

Entrez gene summary

Chromosome

 1

Cytoband

 p13.2

Chromosome location (bp)

 114854803 - 114995370

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000198765 (version 83.38)

Entrez gene

 6847

UniProt

 Q15431 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15431

Antibodypedia

 SYCP1 antibodies

PROTEIN BROWSER
SYCP1-001
SYCP1-002
SYCP1-003
SYCP1-201
SYCP1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SYCP1-001
ENSP00000358535
ENST00000369522
Q15431 [Direct mapping]
Synaptonemal complex protein 1
A0A024R0I2 [Target identity:100%; Query identity:100%]
Synaptonemal complex protein 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000711 [meiotic DNA repair synthesis]
GO:0000794 [condensed nuclear chromosome]
GO:0000795 [synaptonemal complex]
GO:0000801 [central element]
GO:0000802 [transverse filament]
GO:0001673 [male germ cell nucleus]
GO:0003677 [DNA binding]
GO:0005515 [protein binding]
GO:0005694 [chromosome]
GO:0007130 [synaptonemal complex assembly]
GO:0007131 [reciprocal meiotic recombination]
GO:0007283 [spermatogenesis]
GO:0032880 [regulation of protein localization]
GO:0035092 [sperm chromatin condensation]
GO:0051026 [chiasma assembly]
GO:0051301 [cell division]
GO:0051878 [lateral element assembly]
Show all
 976 aa
114.2 kDa 		No 0
SYCP1-002
ENSP00000358531
ENST00000369518
Q15431 [Direct mapping]
Synaptonemal complex protein 1
A0A024R0I2 [Target identity:100%; Query identity:100%]
Synaptonemal complex protein 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000795 [synaptonemal complex]
GO:0003677 [DNA binding]
GO:0007130 [synaptonemal complex assembly]
GO:0007131 [reciprocal meiotic recombination]
GO:0007283 [spermatogenesis]
GO:0051301 [cell division]
Show all
 976 aa
114.2 kDa 		No 0
SYCP1-003
ENSP00000410011
ENST00000455987
Q5VXJ5 [Direct mapping]
Synaptonemal complex protein 1
Show all
Predicted intracellular proteins
Show all
GO:0000795 [synaptonemal complex]
GO:0007130 [synaptonemal complex assembly]
Show all
 792 aa
93.1 kDa 		No 0
SYCP1-201
ENSP00000482532
ENST00000613524
A0A087WZC3 [Direct mapping]
Synaptonemal complex protein 1
Show all
Predicted intracellular proteins
Show all
GO:0000795 [synaptonemal complex]
GO:0007130 [synaptonemal complex assembly]
Show all
 951 aa
111.2 kDa 		No 0
SYCP1-202
ENSP00000480997
ENST00000618516
Q15431 [Direct mapping]
Synaptonemal complex protein 1
A0A024R0I2 [Target identity:100%; Query identity:100%]
Synaptonemal complex protein 1, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Show all
GO:0000795 [synaptonemal complex]
GO:0003677 [DNA binding]
GO:0007130 [synaptonemal complex assembly]
GO:0007131 [reciprocal meiotic recombination]
GO:0007283 [spermatogenesis]
GO:0051301 [cell division]
Show all
 976 aa
114.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.