Expression of KIAA0753 in cancer - Summary - The Human Protein Atlas

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KIAA0753

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KIAA0753
Gene description	KIAA0753
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA023057 , HPA023494
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

Pancreatic cancer

STAINING SUMMARY

HPA023057	HPA023494

GENE INFORMATION
Gene name	KIAA0753
Synonyms
Description	KIAA0753 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	p13.1
Chromosome location (bp)	6578148 - 6640927
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000198920 (version 83.38)
Entrez gene	9851
UniProt	Q2KHM9 (UniProt - Evidence at protein level)
neXtProt	NX_Q2KHM9
Antibodypedia	KIAA0753 antibodies

PROTEIN BROWSER

KIAA0753-001	KIAA0753-002	KIAA0753-005	KIAA0753-006	KIAA0753-011

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KIAA0753-001 ENSP00000355250 ENST00000361413	Q2KHM9 [Direct mapping] Uncharacterized protein KIAA0753 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] Show all	967 aa 109.4 kDa	No	0
KIAA0753-002 ENSP00000460050 ENST00000572370	Q2KHM9 [Direct mapping] Uncharacterized protein KIAA0753 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005813 [centrosome] Show all	668 aa 75.1 kDa	No	0
KIAA0753-005 ENSP00000458983 ENST00000571642	I3L1P2 [Direct mapping] Uncharacterized protein KIAA0753 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		87 aa 9.6 kDa	No	0
KIAA0753-006 ENSP00000458247 ENST00000573033	I3L0P7 [Direct mapping] Uncharacterized protein KIAA0753 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		72 aa 8.1 kDa	No	0
KIAA0753-011 ENSP00000460156 ENST00000576281	I3L341 [Direct mapping] Uncharacterized protein KIAA0753 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		129 aa 14.6 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.