Expression of OXLD1 in cancer - Summary - The Human Protein Atlas

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OXLD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OXLD1
Gene description	Oxidoreductase-like domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (A549)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 2 antibodies. HPA056878 , HPA057019
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PROGNOSTIC SUMMARY
Prognostic marker in cervical cancer (favourable).
Cervical cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA056878	HPA057019

GENE INFORMATION
Gene name	OXLD1 (HGNC Symbol)
Synonyms	C17orf90, MGC104712
Description	Oxidoreductase-like domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.3
Chromosome location (bp)	81665036 - 81666635
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204237 (version 83.38)
Entrez gene	339229
UniProt	Q5BKU9 (UniProt - Evidence at transcript level)
neXtProt	NX_Q5BKU9
Antibodypedia	OXLD1 antibodies

PROTEIN BROWSER

OXLD1-001	OXLD1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OXLD1-001 ENSP00000363873 ENST00000374741	Q5BKU9 [Direct mapping] Oxidoreductase-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005739 [mitochondrion] Show all	147 aa 15.9 kDa	No	0
OXLD1-006 ENSP00000466256 ENST00000571503	I3L208 [Direct mapping] HCG1644378, isoform CRA_a; Oxidoreductase-like domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		92 aa 9.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.