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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ABCF1
  • TISSUE

  • premium

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ABCF1

Gene description

ATP-binding cassette, sub-family F (GCN20), member 1

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Mixed
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Pending external verification.

Reliability score

Approved based on 1 antibody.
HPA017578
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Gallbladder

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

ABCF1 (HGNC Symbol)

Synonyms

ABC50, EST123147

Description

ATP-binding cassette, sub-family F (GCN20), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process. [provided by RefSeq, Jul 2008]

Chromosome

6

Cytoband

p21.33

Chromosome location (bp)

30571376 - 30597179

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000204574 (version 83.38)

Entrez gene

23

UniProt

Q8NE71 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NE71

Antibodypedia

ABCF1 antibodies

PROTEIN BROWSER

ABCF1-001
ABCF1-002
ABCF1-003
ABCF1-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCF1-001
ENSP00000313603
ENST00000326195
Q8NE71 [Direct mapping]
ATP-binding cassette sub-family F member 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006954 [inflammatory response]
GO:0008135 [translation factor activity, RNA binding]
GO:0008494 [translation activator activity]
GO:0016020 [membrane]
GO:0016887 [ATPase activity]
GO:0042788 [polysomal ribosome]
GO:0043022 [ribosome binding]
GO:0044822 [poly(A) RNA binding]
GO:0045727 [positive regulation of translation]
GO:0055085 [transmembrane transport]
Show all
845 aa
95.9 kDa
No 0
ABCF1-002
ENSP00000365728
ENST00000376545
Q8NE71 [Direct mapping]
ATP-binding cassette sub-family F member 1
Q2L6I2 [Target identity:100%; Query identity:100%]
ABC50 protein; ATP-binding cassette, sub-family F (GCN20), member 1; ATP-binding cassette, sub-family F (GCN20), member 1, isoform CRA_a
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005635 [nuclear envelope]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006954 [inflammatory response]
GO:0008135 [translation factor activity, RNA binding]
GO:0008494 [translation activator activity]
GO:0016020 [membrane]
GO:0016887 [ATPase activity]
GO:0042788 [polysomal ribosome]
GO:0043022 [ribosome binding]
GO:0044822 [poly(A) RNA binding]
GO:0045727 [positive regulation of translation]
GO:0055085 [transmembrane transport]
Show all
807 aa
91.7 kDa
No 0
ABCF1-003
ENSP00000405512
ENST00000441867
Q5STZ8 [Direct mapping]
ATP-binding cassette sub-family F member 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
Show all
340 aa
38.4 kDa
No 0
ABCF1-006
ENSP00000440893
ENST00000468958
F5GYK6 [Direct mapping]
ATP-binding cassette sub-family F member 1
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005737 [cytoplasm]
Show all
105 aa
11.7 kDa
No 0

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