Expression of FAM153C in cancer - Summary - The Human Protein Atlas

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FAM153C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	FAM153C
Gene description	Family with sequence similarity 153, member C
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (renal cancer)
HPA (cell line):	Cell line enhanced (U-2 OS)
HPA (normal tissue):	Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 3 antibodies. HPA042585 , HPA046691 , HPA052337
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (renal cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042585	HPA046691	HPA052337

GENE INFORMATION
Gene name	FAM153C (HGNC Symbol)
Synonyms	NY-REN-7-like
Description	Family with sequence similarity 153, member C (HGNC Symbol)
Entrez gene summary
Chromosome	5
Cytoband	q35.3
Chromosome location (bp)	178006405 - 178055559
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000204677 (version 83.38)
Entrez gene
UniProt	Q494X1 (UniProt - Evidence at protein level)
neXtProt	NX_Q494X1
Antibodypedia	FAM153C antibodies

PROTEIN BROWSER

FAM153C-001	FAM153C-002	FAM153C-004	FAM153C-005	FAM153C-012	FAM153C-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAM153C-001 ENSP00000381177 ENST00000398106	Q494X1 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	114 aa 12.9 kDa	No	0
FAM153C-002 ENSP00000424623 ENST00000507848	Q494X1 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	144 aa 16.6 kDa	No	0
FAM153C-004 ENSP00000422293 ENST00000511856	D6RCA3 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all		176 aa 20.2 kDa	No	0
FAM153C-005 ENSP00000426621 ENST00000511189	D6RF56 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all		173 aa 19.8 kDa	No	0
FAM153C-012 ENSP00000423403 ENST00000504530	D6RA46 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all		39 aa 4.9 kDa	No	0
FAM153C-201 ENSP00000481919 ENST00000620373	Q494X1 [Direct mapping] Protein FAM153C Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] Show all	144 aa 16.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.