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PNMAL2

GENERAL INFORMATION

Gene name

 PNMAL2

Gene description

 Paraneoplastic Ma antigen family-like 2

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Group enriched (adrenal gland, cerebral cortex)
GTEx:Not detected
FANTOM5:Tissue enhanced (brain, hippocampus)

Protein evidence

 Evidence at protein level

Protein expression

 Mainly cytoplasmic expression in a group of tissues, including CNS and adrenal gland.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Reliability score

 Approved based on 1 antibody.
HPA054810
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Group enriched (adrenal gland, cerebral cortex)
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin05101520253035TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin0246810RPKM
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (brain, hippocampus)
Pituitary glandBrainHippocampusCaudateCerebellumThyroid glandAppendixLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusSmall intestineColonKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumOvaryPlacentaAdipose tissueRetina020406080100120140Tags Per Million

GENE INFORMATION

Gene name

 PNMAL2 (HGNC Symbol)

Synonyms

 KIAA1183

Description

 Paraneoplastic Ma antigen family-like 2 (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 q13.32

Chromosome location (bp)

 46486906 - 46496498

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000204851 (version 83.38)

Entrez gene

 57469

UniProt

 Q9ULN7 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9ULN7

Antibodypedia

 PNMAL2 antibodies

PROTEIN BROWSER
PNMAL2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PNMAL2-001
ENSP00000473036
ENST00000599531
Q9ULN7 [Direct mapping]
PNMA-like protein 2
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
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 635 aa
68.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.