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GRXCR2

GENERAL INFORMATION

Gene name

 GRXCR2

Gene description

 Glutaredoxin, cysteine rich 2

Protein class

 Disease related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Tissue enhanced (testis)

Protein evidence

 Evidence at transcript level

Protein expression

 Estimation of protein expression could not be performed. View primary data.

DATA RELIABILITY

Data reliability
description

 RNA-based expert annotation gave inconclusive results. Pending external verification. No internal RNA expression data available for correlation.

Reliability score

 Uncertain based on 1 antibody.
HPA059421
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate

PROTEIN EXPRESSION OVERVIEW
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)

GENE INFORMATION

Gene name

 GRXCR2 (HGNC Symbol)

Synonyms

 DFNB101

Description

 Glutaredoxin, cysteine rich 2 (HGNC Symbol)

Entrez gene summary

 This gene encodes a protein containing a glutaredoxin domain, which functions in protein S-glutathionylation. A mutation in this gene was found in a family with autoosomal recessive nonsyndromic sensorineural deafness-101. [provided by RefSeq, Jun 2014]

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 145859733 - 145872968

Protein evidence

 Evidence at transcript level (all genes)

Ensembl

 ENSG00000204928 (version 83.38)

Entrez gene

 643226

UniProt

 A6NFK2 (UniProt - Inferred from homology)

neXtProt

 NX_A6NFK2

Antibodypedia

 GRXCR2 antibodies

PROTEIN BROWSER
GRXCR2-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GRXCR2-001
ENSP00000367214
ENST00000377976
A6NFK2 [Direct mapping]
Glutaredoxin domain-containing cysteine-rich protein 2
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Predicted intracellular proteins
Disease related genes
Show all
GO:0005902 [microvillus]
GO:0007605 [sensory perception of sound]
GO:0031072 [heat shock protein binding]
GO:0032420 [stereocilium]
GO:0051082 [unfolded protein binding]
Show all
 248 aa
28.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.