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ARHGEF33

GENERAL INFORMATION

Gene name

 ARHGEF33

Gene description

 Rho guanine nucleotide exchange factor (GEF) 33

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 4
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enhanced (testis)
GTEx:Tissue enhanced (cerebellum)
FANTOM5:Tissue enriched (cerebellum)

Protein evidence

 Evidence at protein level

Protein expression

 Distinct cytoplasmic expression in cerebellum.

DATA RELIABILITY

Data reliability
description

 Pending external verification. Paired antibodies with high similarity support the expression profile.

Reliability score

 Supported based on 2 antibodies.
HPA034661 , HPA041051
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Cerebellum

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (cerebellum)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (cerebellum)

GENE INFORMATION

Gene name

 ARHGEF33

Synonyms

Description

 Rho guanine nucleotide exchange factor (GEF) 33 (HGNC Symbol)

Entrez gene summary

Chromosome

 2

Cytoband

 p22.1

Chromosome location (bp)

 38889880 - 38975449

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000214694 (version 83.38)

Entrez gene

 100271715

UniProt

 A8MVX0 (UniProt - Evidence at transcript level)

neXtProt

 NX_A8MVX0

Antibodypedia

 ARHGEF33 antibodies

PROTEIN BROWSER
ARHGEF33-001
ARHGEF33-004
ARHGEF33-006
ARHGEF33-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
ARHGEF33-001
ENSP00000387020
ENST00000409978
A8MVX0 [Direct mapping]
Rho guanine nucleotide exchange factor 33
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   THUMBUP predicted membrane proteins
Predicted intracellular proteins
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GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
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 870 aa
97.5 kDa 		No 0
ARHGEF33-004
ENSP00000413620
ENST00000433605
H7C3S6 [Direct mapping]
Rho guanine nucleotide exchange factor 33
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Predicted intracellular proteins
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 108 aa
12.2 kDa 		No 0
ARHGEF33-006
ENSP00000399688
ENST00000411874
H7C1C9 [Direct mapping]
Rho guanine nucleotide exchange factor 33
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Predicted intracellular proteins
Show all
 109 aa
12.2 kDa 		No 0
ARHGEF33-201
ENSP00000381780
ENST00000398800
A8MVX0 [Direct mapping]
Rho guanine nucleotide exchange factor 33
Show all
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0005089 [Rho guanyl-nucleotide exchange factor activity]
GO:0035023 [regulation of Rho protein signal transduction]
GO:0043547 [positive regulation of GTPase activity]
Show all
 870 aa
97.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.