Cell atlas - RPL17-C18orf32 - The Human Protein Atlas

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RPL17-C18orf32

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Endoplasmic reticulum

Human cell
	Cytosol
	Endoplasmic Reticulum

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GENERAL INFORMATION
Gene name	RPL17-C18orf32
Gene description	RPL17-C18orf32 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Endoplasmic reticulum (supported), Cytosol (supported)

DATA RELIABILITY
Reliability score	Supported based on 2 antibodies. HPA043724 , HPA046385
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the cytosol & endoplasmic reticulum. In addition localized to the nucleoli. Caution: Based on antibodies targeting proteins from multiple genes.

Main location

Endoplasmic reticulum (supported), Cytosol (supported)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA043724	A-431	Endoplasmic reticulum
HPA043724	A-431	Cytosol
HPA043724	U-2 OS	Endoplasmic reticulum
HPA043724	U-2 OS	Cytosol
HPA043724	U-251 MG	Endoplasmic reticulum
HPA043724	U-251 MG	Cytosol
HPA046385	HEK 293	Endoplasmic reticulum
HPA046385	HEK 293	Cytosol
HPA046385	Hep G2	Endoplasmic reticulum
HPA046385	Hep G2	Cytosol
HPA046385	U-2 OS	Nucleoli
		Endoplasmic reticulum
		Cytosol

GENE INFORMATION
Gene name	RPL17-C18orf32
Synonyms
Description	RPL17-C18orf32 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded isoforms share sequence identity with the RPL17 protein, but they include frameshifted C-terminal regions derived from the downstream gene exons. [provided by RefSeq, Dec 2010]
Chromosome	18
Cytoband	q21.1
Chromosome location (bp)	49481681 - 49492479
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215472 (version 83.38)
Entrez gene	100526842
UniProt
neXtProt
Antibodypedia	RPL17-C18orf32 antibodies

PROTEIN BROWSER

RPL17-C18orf32-001	RPL17-C18orf32-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPL17-C18orf32-001 ENSP00000463379 ENST00000584895	A0A0A6YYL6 [Direct mapping] Protein RPL17-C18orf32 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002181 [cytoplasmic translation] GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0015934 [large ribosomal subunit] GO:0022625 [cytosolic large ribosomal subunit] GO:0044822 [poly(A) RNA binding] Show all	228 aa 26.4 kDa	No	0
RPL17-C18orf32-003 ENSP00000352143 ENST00000332968	A0A0A0MRF8 [Direct mapping] Protein RPL17-C18orf32; UPF0729 protein C18orf32 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002181 [cytoplasmic translation] GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0015934 [large ribosomal subunit] GO:0022625 [cytosolic large ribosomal subunit] GO:0044822 [poly(A) RNA binding] Show all	190 aa 22.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.