Expression of RPL17-C18orf32 in cancer - Summary - The Human Protein Atlas

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RPL17-C18orf32

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RPL17-C18orf32
Gene description	RPL17-C18orf32 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA043724 , HPA046385
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA043724	HPA046385

GENE INFORMATION
Gene name	RPL17-C18orf32
Synonyms
Description	RPL17-C18orf32 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring RPL17 (ribosomal protein L17) and C18orf32 (chromosome 18 open reading frame 32) genes. Alternative splicing results in multiple transcript variants. The encoded isoforms share sequence identity with the RPL17 protein, but they include frameshifted C-terminal regions derived from the downstream gene exons. [provided by RefSeq, Dec 2010]
Chromosome	18
Cytoband	q21.1
Chromosome location (bp)	49481681 - 49492479
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000215472 (version 83.38)
Entrez gene	100526842
UniProt
neXtProt
Antibodypedia	RPL17-C18orf32 antibodies

PROTEIN BROWSER

RPL17-C18orf32-001	RPL17-C18orf32-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RPL17-C18orf32-001 ENSP00000463379 ENST00000584895	A0A0A6YYL6 [Direct mapping] Protein RPL17-C18orf32 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002181 [cytoplasmic translation] GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0015934 [large ribosomal subunit] GO:0022625 [cytosolic large ribosomal subunit] GO:0044822 [poly(A) RNA binding] Show all	228 aa 26.4 kDa	No	0
RPL17-C18orf32-003 ENSP00000352143 ENST00000332968	A0A0A0MRF8 [Direct mapping] Protein RPL17-C18orf32; UPF0729 protein C18orf32 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0002181 [cytoplasmic translation] GO:0003735 [structural constituent of ribosome] GO:0005622 [intracellular] GO:0005840 [ribosome] GO:0006412 [translation] GO:0015934 [large ribosomal subunit] GO:0022625 [cytosolic large ribosomal subunit] GO:0044822 [poly(A) RNA binding] Show all	190 aa 22.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.