Cell atlas - AP4M1 - The Human Protein Atlas

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AP4M1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	AP4M1
Gene description	Adaptor-related protein complex 4, mu 1 subunit
Protein class	Disease related genes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	8
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	AP4M1 (HGNC Symbol)
Synonyms	MU-4, MU-ARP2, SPG50
Description	Adaptor-related protein complex 4, mu 1 subunit (HGNC Symbol)
Entrez gene summary	This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system. [provided by RefSeq, Jul 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	100101549 - 100110345
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000221838 (version 83.38)
Entrez gene	9179
UniProt	O00189 (UniProt - Evidence at protein level)
neXtProt	NX_O00189
Antibodypedia	AP4M1 antibodies

PROTEIN BROWSER

AP4M1-001	AP4M1-002	AP4M1-006	AP4M1-008	AP4M1-010	AP4M1-014	AP4M1-015	AP4M1-016

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AP4M1-001 ENSP00000352603 ENST00000359593	O00189 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000138 [Golgi trans cisterna] GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005802 [trans-Golgi network] GO:0005905 [coated pit] GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006895 [Golgi to endosome transport] GO:0016192 [vesicle-mediated transport] GO:0030119 [AP-type membrane coat adaptor complex] GO:0030131 [clathrin adaptor complex] GO:0031904 [endosome lumen] GO:0032588 [trans-Golgi network membrane] GO:0061024 [membrane organization] GO:0070062 [extracellular exosome] Show all	453 aa 50 kDa	No	0
AP4M1-002 ENSP00000401613 ENST00000438383	C9JWL4 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0016192 [vesicle-mediated transport] GO:0030131 [clathrin adaptor complex] Show all	311 aa 34.5 kDa	No	0
AP4M1-006 ENSP00000403663 ENST00000429084	C9JC87 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0016192 [vesicle-mediated transport] GO:0030131 [clathrin adaptor complex] Show all	460 aa 50.7 kDa	No	0
AP4M1-008 ENSP00000406676 ENST00000422582	C9IZL5 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0016192 [vesicle-mediated transport] GO:0030131 [clathrin adaptor complex] Show all	325 aa 35.7 kDa	No	0
AP4M1-010 ENSP00000414286 ENST00000439416	C9JMG3 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0016192 [vesicle-mediated transport] GO:0030131 [clathrin adaptor complex] Show all	266 aa 29.7 kDa	No	0
AP4M1-014 ENSP00000393723 ENST00000445295	H7C0A0 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		138 aa 15.6 kDa	No	0
AP4M1-015 ENSP00000412185 ENST00000421755	O00189 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Disease related genes Protein evidence (Ezkurdia et al 2014) Show all	GO:0000138 [Golgi trans cisterna] GO:0005215 [transporter activity] GO:0005515 [protein binding] GO:0005802 [trans-Golgi network] GO:0005905 [coated pit] GO:0006810 [transport] GO:0006886 [intracellular protein transport] GO:0006892 [post-Golgi vesicle-mediated transport] GO:0006895 [Golgi to endosome transport] GO:0016192 [vesicle-mediated transport] GO:0030119 [AP-type membrane coat adaptor complex] GO:0030131 [clathrin adaptor complex] GO:0031904 [endosome lumen] GO:0032588 [trans-Golgi network membrane] GO:0061024 [membrane organization] GO:0070062 [extracellular exosome] Show all	453 aa 50 kDa	No	0
AP4M1-016 ENSP00000391585 ENST00000450807	H7BZV3 [Direct mapping] AP-4 complex subunit mu-1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0006886 [intracellular protein transport] GO:0016192 [vesicle-mediated transport] GO:0030131 [clathrin adaptor complex] Show all	160 aa 17.9 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.