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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

Score

Score

Antibodies

Column

 
 
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PSG7
  • TISSUE

  • CELL

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

PSG7

Gene description

Pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene)

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enhanced (placenta, skin)
GTEx:Not detected
FANTOM5:Tissue enriched (placenta)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in trophoblasts.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Reliability score

Approved based on 1 antibody.
HPA046327
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Placenta

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (placenta, skin)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Not detected
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (placenta)

GENE INFORMATION

Gene name

PSG7

Synonyms

Description

Pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) (HGNC Symbol)

Entrez gene summary

This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014]

Chromosome

19

Cytoband

q13.31

Chromosome location (bp)

42906822 - 43082671

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000221878 (version 83.38)

Entrez gene

5676

UniProt

neXtProt

Antibodypedia

PSG7 antibodies

PROTEIN BROWSER

PSG7-001
PSG7-003
PSG7-006
PSG7-201
PSG7-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSG7-001
ENSP00000421986
ENST00000406070
A0A087WSZ1 [Direct mapping]
Putative pregnancy-specific beta-1-glycoprotein 7
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
Show all
419 aa
47 kDa
Yes 0
PSG7-003
ENSP00000470856
ENST00000446844
A0A087WT09 [Direct mapping]
Putative pregnancy-specific beta-1-glycoprotein 7
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
Show all
426 aa
47.7 kDa
Yes 0
PSG7-006
ENSP00000485117
ENST00000623675
A0A096LNM5 [Direct mapping]
Putative pregnancy-specific beta-1-glycoprotein 7
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
Show all
297 aa
33.4 kDa
No 0
PSG7-201
ENSP00000480429
ENST00000617049
A0A087WWQ7 [Direct mapping]
Putative pregnancy-specific beta-1-glycoprotein 7
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
Show all
426 aa
47.7 kDa
Yes 0
PSG7-202
ENSP00000478484
ENST00000618424
A0A087WU99 [Direct mapping]
Putative pregnancy-specific beta-1-glycoprotein 7
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Show all
GO:0005515 [protein binding]
Show all
419 aa
47.2 kDa
Yes 0

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