Expression of RP11-166B2.1 in cancer - Summary - The Human Protein Atlas

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RP11-166B2.1

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	RP11-166B2.1
Gene description	Putative NPIP-like protein LOC729978
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (RPMI-8226, U-266/70)
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Supported based on 1 antibody. HPA053611
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA053611

GENE INFORMATION
Gene name	RP11-166B2.1
Synonyms
Description	Putative NPIP-like protein LOC729978 (UniProtKB/Swiss-Prot)
Entrez gene summary
Chromosome	16
Cytoband	p13.13
Chromosome location (bp)	11927373 - 11976643
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000234719 (version 83.38)
Entrez gene
UniProt	A6NJ64 (UniProt - Uncertain)
neXtProt	NX_A6NJ64
Antibodypedia	RP11-166B2.1 antibodies

PROTEIN BROWSER

RP11-166B2.1-001	RP11-166B2.1-003	RP11-166B2.1-007	RP11-166B2.1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RP11-166B2.1-001 ENSP00000382101 ENST00000399147	A6NJ64 [Target identity:100%; Query identity:100%] Putative NPIP-like protein LOC729978 A0A0A6YYH2 [Direct mapping] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0005634 [nucleus] Show all	397 aa 45.6 kDa	No	1
RP11-166B2.1-003 ENSP00000442069 ENST00000538896	F5H898 [Direct mapping] Uncharacterized protein Show all	Predicted intracellular proteins Show all		35 aa 4.1 kDa	No	0
RP11-166B2.1-007 ENSP00000448752 ENST00000547494	F8VY45 [Direct mapping] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		307 aa 35.3 kDa	No	1
RP11-166B2.1-201 ENSP00000478897 ENST00000620285	A0A087WUS9 [Direct mapping] Uncharacterized protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all		250 aa 29.3 kDa	Yes	1

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.