Tissue expression of ARHGDIG - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	ARHGDIG
Gene description	Rho GDP dissociation inhibitor (GDI) gamma
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (cerebral cortex, duodenum)
GTEx:	Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, pancreas)
FANTOM5:	Group enriched (brain, caudate, cerebellum, hippocampus, pancreas, small intestine)

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (cerebral cortex, duodenum)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (caudate, cerebellum, cerebral cortex, hippocampus, hypothalamus, pancreas)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (brain, caudate, cerebellum, hippocampus, pancreas, small intestine)

GENE INFORMATION
Gene name	ARHGDIG (HGNC Symbol)
Synonyms	RHOGDI-3
Description	Rho GDP dissociation inhibitor (GDI) gamma (HGNC Symbol)
Entrez gene summary	The GDP-dissociation inhibitors (GDIs) play a primary role in modulating the activation of GTPases by inhibiting the exchange of GDP for GTP. See ARHGDIB (MIM 602843).[supplied by OMIM, Nov 2010]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	268727 - 283010
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000242173 (version 83.38)
Entrez gene	398
UniProt	Q99819 (UniProt - Evidence at protein level)
neXtProt	NX_Q99819
Antibodypedia	ARHGDIG antibodies

PROTEIN BROWSER

ARHGDIG-001	ARHGDIG-002	ARHGDIG-004	ARHGDIG-005	ARHGDIG-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ARHGDIG-001 ENSP00000219409 ENST00000219409	Q99819 [Direct mapping] Rho GDP-dissociation inhibitor 3 F1T0H7 [Target identity:100%; Query identity:100%] HCG1985507, isoform CRA_a; Rho GDP-dissociation inhibitor 3 Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0005092 [GDP-dissociation inhibitor activity] GO:0005094 [Rho GDP-dissociation inhibitor activity] GO:0005096 [GTPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0007162 [negative regulation of cell adhesion] GO:0007264 [small GTPase mediated signal transduction] GO:0007266 [Rho protein signal transduction] GO:0016020 [membrane] GO:0016023 [cytoplasmic membrane-bounded vesicle] GO:0030695 [GTPase regulator activity] GO:0032880 [regulation of protein localization] GO:0043547 [positive regulation of GTPase activity] GO:0051056 [regulation of small GTPase mediated signal transduction] Show all	225 aa 25.1 kDa	No	0
ARHGDIG-002 ENSP00000410541 ENST00000414650	C9J3B5 [Direct mapping] Rho GDP-dissociation inhibitor 3 Show all	Predicted intracellular proteins Show all	GO:0005094 [Rho GDP-dissociation inhibitor activity] GO:0005737 [cytoplasm] GO:0050790 [regulation of catalytic activity] Show all	116 aa 13.4 kDa	No	0
ARHGDIG-004 ENSP00000404435 ENST00000447871	A2ID99 [Direct mapping] Rho GDP dissociation inhibitor (GDI) gamma; Rho GDP-dissociation inhibitor 3 Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0005094 [Rho GDP-dissociation inhibitor activity] GO:0005737 [cytoplasm] GO:0050790 [regulation of catalytic activity] Show all	178 aa 19.6 kDa	No	0
ARHGDIG-005 ENSP00000408037 ENST00000412541	C9JR26 [Direct mapping] Rho GDP-dissociation inhibitor 3 Show all	Predicted intracellular proteins Show all	GO:0005094 [Rho GDP-dissociation inhibitor activity] GO:0005737 [cytoplasm] GO:0050790 [regulation of catalytic activity] Show all	76 aa 8.3 kDa	No	0
ARHGDIG-006 ENSP00000397395 ENST00000435035	C9J9L9 [Direct mapping] Rho GDP-dissociation inhibitor 3 Show all	Predicted intracellular proteins Show all	GO:0005094 [Rho GDP-dissociation inhibitor activity] GO:0005737 [cytoplasm] GO:0050790 [regulation of catalytic activity] Show all	136 aa 14.9 kDa	No	0