Expression of SYNJ2BP-COX16 in cancer - Summary - The Human Protein Atlas

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SYNJ2BP-COX16

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	SYNJ2BP-COX16
Gene description	SYNJ2BP-COX16 readthrough
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Mixed
HPA (normal tissue):	Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Granular cytoplasmic expression, most abundant gastrointestinal tract.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.
Reliability score	Approved based on 2 antibodies. HPA000866 , HPA062659
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA000866	HPA062659

GENE INFORMATION
Gene name	SYNJ2BP-COX16
Synonyms
Description	SYNJ2BP-COX16 readthrough (HGNC Symbol)
Entrez gene summary	This locus represents naturally occurring read-through transcription between the neighboring SYNJ2BP (synaptojanin 2 binding protein) and COX16 (COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)) genes on chromosome 14. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2011]
Chromosome	14
Cytoband	q24.2
Chromosome location (bp)	70326064 - 70417074
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000258644 (version 83.38)
Entrez gene	100529257
UniProt
neXtProt
Antibodypedia	SYNJ2BP-COX16 antibodies

PROTEIN BROWSER

SYNJ2BP-COX16-001	SYNJ2BP-COX16-002	SYNJ2BP-COX16-003	SYNJ2BP-COX16-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SYNJ2BP-COX16-001 ENSP00000480746 ENST00000555276	A0A087WX56 [Direct mapping] Protein SYNJ2BP-COX16 Show all	Predicted intracellular proteins Show all	GO:0031966 [mitochondrial membrane] Show all	54 aa 6.5 kDa	No	0
SYNJ2BP-COX16-002 ENSP00000482133 ENST00000621525	A0A087WYV9 [Direct mapping] Protein SYNJ2BP-COX16 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0031966 [mitochondrial membrane] Show all	182 aa 20.5 kDa	No	0
SYNJ2BP-COX16-003 ENSP00000478757 ENST00000617196	A0A087WUM0 [Direct mapping] Protein SYNJ2BP-COX16 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0031966 [mitochondrial membrane] Show all	186 aa 20.8 kDa	No	0
SYNJ2BP-COX16-005 ENSP00000484161 ENST00000617124	A0A087X1F5 [Direct mapping] Protein SYNJ2BP-COX16 Show all	Predicted intracellular proteins Show all	GO:0005515 [protein binding] GO:0031966 [mitochondrial membrane] Show all	153 aa 17.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.