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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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OTUD7B
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    TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

OTUD7B

Gene description

OTU deubiquitinase 7B

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Mixed
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General nuclear and cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Reliability score

Supported based on 1 antibody.
HPA027045
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Mixed
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

OTUD7B (HGNC Symbol)

Synonyms

CEZANNE, ZA20D1

Description

OTU deubiquitinase 7B (HGNC Symbol)

Entrez gene summary

Chromosome

1

Cytoband

q21.2

Chromosome location (bp)

149937812 - 150010676

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000264522 (version 83.38)

Entrez gene

56957

UniProt

Q6GQQ9 (UniProt - Evidence at protein level)

neXtProt

NX_Q6GQQ9

Antibodypedia

OTUD7B antibodies

PROTEIN BROWSER

OTUD7B-001
OTUD7B-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

OTUD7B-001
ENSP00000462729
ENST00000581312
Q6GQQ9 [Direct mapping]
OTU domain-containing protein 7B
Show all
Enzymes
   ENZYME proteins
   Hydrolases
   Peptidases
   Cysteine-type peptidases
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0002385 [mucosal immune response]
GO:0003677 [DNA binding]
GO:0004843 [ubiquitin-specific protease activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0008234 [cysteine-type peptidase activity]
GO:0008270 [zinc ion binding]
GO:0016579 [protein deubiquitination]
GO:0032717 [negative regulation of interleukin-8 production]
GO:0035871 [protein K11-linked deubiquitination]
GO:0043124 [negative regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0045088 [regulation of innate immune response]
GO:0050727 [regulation of inflammatory response]
GO:0070530 [K63-linked polyubiquitin binding]
GO:0070536 [protein K63-linked deubiquitination]
GO:0071108 [protein K48-linked deubiquitination]
GO:0071947 [protein deubiquitination involved in ubiquitin-dependent protein catabolic process]
GO:1900181 [negative regulation of protein localization to nucleus]
GO:1990380 [Lys48-specific deubiquitinase activity]
Show all
843 aa
92.5 kDa
No 0
OTUD7B-003
ENSP00000408231
ENST00000417191
Q5SZ59 [Direct mapping]
OTU domain containing 7B; OTU domain-containing protein 7B
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Predicted intracellular proteins
Show all
427 aa
47.6 kDa
No 0

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