Cell atlas - APOC4 - The Human Protein Atlas

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APOC4

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	APOC4
Gene description	Apolipoprotein C-IV
Protein class	Plasma proteins Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (SK-MEL-30, HEL)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SK-MEL-30, HEL) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	APOC4
Synonyms
Description	Apolipoprotein C-IV (HGNC Symbol)
Entrez gene summary	This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is thought to play a role in lipid metabolism. Polymorphisms in this gene may influence circulating lipid levels and may be associated with coronary artery disease risk. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring downstream apolipoprotein C-II (APOC2) gene. [provided by RefSeq, Mar 2011]
Chromosome	19
Cytoband	q13.32
Chromosome location (bp)	44942238 - 44945496
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000267467 (version 83.38)
Entrez gene	346
UniProt	P55056 (UniProt - Evidence at protein level)
neXtProt	NX_P55056
Antibodypedia	APOC4 antibodies

PROTEIN BROWSER

APOC4-001	APOC4-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APOC4-001 ENSP00000468236 ENST00000592954	P55056 [Direct mapping] Apolipoprotein C-IV Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Plasma proteins Protein evidence (Kim et al 2014) Show all	GO:0005319 [lipid transporter activity] GO:0006629 [lipid metabolic process] GO:0006869 [lipid transport] GO:0010890 [positive regulation of sequestering of triglyceride] GO:0034361 [very-low-density lipoprotein particle] GO:0034364 [high-density lipoprotein particle] GO:0070328 [triglyceride homeostasis] Show all	127 aa 14.6 kDa	Yes	0
APOC4-002 ENSP00000466444 ENST00000591600	K7EMC3 [Direct mapping] Apolipoprotein C-IV Show all	MEMSAT3 predicted membrane proteins THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		73 aa 8.4 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.