Cell atlas - S1PR2 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

S1PR2

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	S1PR2
Gene description	Sphingosine-1-phosphate receptor 2
Protein class	G-protein coupled receptors Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (U-698, WM-115, Daudi)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (U-698, WM-115, Daudi) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	S1PR2 (HGNC Symbol)
Synonyms	AGR16, EDG5, Gpcr13, H218
Description	Sphingosine-1-phosphate receptor 2 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. This protein participates in sphingosine 1-phosphate-induced cell proliferation, survival, and transcriptional activation [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.2
Chromosome location (bp)	10221435 - 10231272
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000267534 (version 83.38)
Entrez gene	9294
UniProt	O95136 (UniProt - Evidence at protein level)
neXtProt	NX_O95136
Antibodypedia	S1PR2 antibodies

PROTEIN BROWSER

S1PR2-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
S1PR2-001 ENSP00000466933 ENST00000590320	O95136 [Direct mapping] Sphingosine 1-phosphate receptor 2 A0A024R7B2 [Target identity:100%; Query identity:100%] Endothelial differentiation, sphingolipid G-protein-coupled receptor, 5, isoform CRA_a Show all	G-protein coupled receptors GPCRs excl olfactory receptors Lysolipids receptors Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins GPCRHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Show all	GO:0000187 [activation of MAPK activity] GO:0001664 [G-protein coupled receptor binding] GO:0003376 [sphingosine-1-phosphate signaling pathway] GO:0004930 [G-protein coupled receptor activity] GO:0005178 [integrin binding] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0008284 [positive regulation of cell proliferation] GO:0008289 [lipid binding] GO:0010800 [positive regulation of peptidyl-threonine phosphorylation] GO:0016021 [integral component of membrane] GO:0031532 [actin cytoskeleton reorganization] GO:0038036 [sphingosine-1-phosphate receptor activity] GO:0046847 [filopodium assembly] GO:0090394 [negative regulation of excitatory postsynaptic potential] GO:1903142 [positive regulation of establishment of endothelial barrier] Show all	353 aa 38.9 kDa	No	7

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.