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Cancer tissues were negative. A rare case of pancreatic and endometrial cancers exhibited moderate to strong staining in fraction of cells.
GENE INFORMATION
Gene name
PIP4K2B (HGNC Symbol)
Synonyms
PIP5K2B, PIP5KIIB, PIP5KIIbeta
Description
Phosphatidylinositol-5-phosphate 4-kinase, type II, beta (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene catalyzes the phosphorylation of phosphatidylinositol-5-phosphate on the fourth hydroxyl of the myo-inositol ring to form phosphatidylinositol-5,4-bisphosphate. This gene is a member of the phosphatidylinositol-5-phosphate 4-kinase family. The encoded protein sequence does not show similarity to other kinases, but the protein does exhibit kinase activity. Additionally, the encoded protein interacts with p55 TNF receptor. [provided by RefSeq, Jul 2008]