Nuclear bodies

Nuclear body is a collective term for several non-membrane-bound nuclear sub-compartments, including but not limited to Cajal bodies, Gemini of Cajal bodies and promyelocytic leukemia bodies (PML). Cajal bodies are involved in RNA splicing whereas PML bodies are thought to perform a multitude of tasks including apoptosis regulation.

Immunofluorescent staining

Nuclear bodies are visible as distinct spots in the nucleoplasm. They can vary in number and size depending on the cell line and the type of nuclear body.

Read more about the nuclear proteome.