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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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RALA
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

RALA

Gene description

V-ral simian leukemia viral oncogene homolog A (ras related)

Protein class

Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Caution, targets protein from more than one gene.

Reliability score

Approved based on 1 antibody.
HPA065232
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

RALA (HGNC Symbol)

Synonyms

RAL

Description

V-ral simian leukemia viral oncogene homolog A (ras related) (HGNC Symbol)

Entrez gene summary

The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins. [provided by RefSeq, Jul 2008]

Chromosome

7

Cytoband

p14.1

Chromosome location (bp)

39623483 - 39708124

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006451 (version 83.38)

Entrez gene

5898

UniProt

P11233 (UniProt - Evidence at protein level)

neXtProt

NX_P11233

Antibodypedia

RALA antibodies

PROTEIN BROWSER

RALA-001
RALA-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RALA-001
ENSP00000005257
ENST00000005257
P11233 [Direct mapping]
Ras-related protein Ral-A
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000910 [cytokinesis]
GO:0001843 [neural tube closure]
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0005925 [focal adhesion]
GO:0006886 [intracellular protein transport]
GO:0006887 [exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0006935 [chemotaxis]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0008152 [metabolic process]
GO:0009986 [cell surface]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0017022 [myosin binding]
GO:0017157 [regulation of exocytosis]
GO:0019003 [GDP binding]
GO:0030139 [endocytic vesicle]
GO:0030496 [midbody]
GO:0030659 [cytoplasmic vesicle membrane]
GO:0031532 [actin cytoskeleton reorganization]
GO:0031625 [ubiquitin protein ligase binding]
GO:0031755 [Edg-2 lysophosphatidic acid receptor binding]
GO:0032154 [cleavage furrow]
GO:0043209 [myelin sheath]
GO:0048011 [neurotrophin TRK receptor signaling pathway]
GO:0051117 [ATPase binding]
GO:0051491 [positive regulation of filopodium assembly]
GO:0051665 [membrane raft localization]
GO:0061024 [membrane organization]
GO:0070062 [extracellular exosome]
Show all
206 aa
23.6 kDa
No 0
RALA-003
ENSP00000388975
ENST00000436179
C9JPE8 [Direct mapping]
Ras-related protein Ral-A
Show all
Predicted intracellular proteins
RAS pathway related proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005886 [plasma membrane]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007265 [Ras protein signal transduction]
GO:0008152 [metabolic process]
GO:0015031 [protein transport]
GO:0016020 [membrane]
Show all
101 aa
11.2 kDa
No 0

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