Cell atlas - WDR37 - The Human Protein Atlas

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WDR37

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Centrosome
	Cytosol
	Intermediate filaments

Human cell
	Centrosome
	Cytosol
	Intermediate Filaments

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GENERAL INFORMATION
Gene name	WDR37
Gene description	WD repeat domain 37
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the cytosol, intermediate filaments & centrosome.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Intermediate filaments (uncertain), Centrosome (uncertain), Cytosol (uncertain)
Single-cell variation	Single-cell variation in protein expression observed.

DATA RELIABILITY
Reliability score	Uncertain based on 2 antibodies. HPA037376 , HPA037565
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the cytosol, intermediate filaments & centrosome.

Main location

Intermediate filaments (uncertain), Centrosome (uncertain), Cytosol (uncertain)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location	Single-cell variation
HPA037376	A-431	Centrosome
HPA037376	A-431	Cytosol
HPA037376	U-2 OS	Centrosome
HPA037376	U-2 OS	Cytosol
HPA037376	U-251 MG	Centrosome
HPA037565	A-431	Intermediate filaments	Intensity
HPA037565	U-2 OS	Aggresome
HPA037565	U-251 MG	No staining

GENE INFORMATION
Gene name	WDR37 (HGNC Symbol)
Synonyms	KIAA0982
Description	WD repeat domain 37 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]
Chromosome	10
Cytoband	p15.3
Chromosome location (bp)	1049538 - 1132297
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000047056 (version 83.38)
Entrez gene	22884
UniProt	Q9Y2I8 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y2I8
Antibodypedia	WDR37 antibodies

PROTEIN BROWSER

WDR37-001	WDR37-002	WDR37-004	WDR37-005	WDR37-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
WDR37-001 ENSP00000350954 ENST00000358220	Q9Y2I8 [Direct mapping] WD repeat-containing protein 37 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	494 aa 54.7 kDa	No	0
WDR37-002 ENSP00000263150 ENST00000263150	Q9Y2I8 [Direct mapping] WD repeat-containing protein 37 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	494 aa 54.7 kDa	No	0
WDR37-004 ENSP00000370730 ENST00000381329	E7EQ49 [Direct mapping] WD repeat-containing protein 37 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	249 aa 27.4 kDa	No	0
WDR37-005 ENSP00000404346 ENST00000436154	C9JGR9 [Direct mapping] WD repeat-containing protein 37 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	209 aa 22.9 kDa	No	0
WDR37-201 ENSP00000478057 ENST00000620998	A0A087WTQ2 [Direct mapping] WD repeat-containing protein 37 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	263 aa 29.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.