Cell atlas - MTMR1 - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MTMR1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm
	Plasma membrane
	Vesicles

Human cell
	Nucleoplasm
	Plasma Membrane
	Vesicles

Please wait until image is loaded before changing channels

GENERAL INFORMATION
Gene name	MTMR1
Gene description	Myotubularin related protein 1
Protein class	Enzymes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	10
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the plasma membrane. In addition localized to the nucleoplasm & vesicles.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Plasma membrane (approved)
Additional location	In addition localized to the Nucleoplasm (approved), Vesicles (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA002977
	SHOW MORE

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the plasma membrane. In addition localized to the nucleoplasm & vesicles.

Main location

Plasma membrane (approved)

Additional location

Nucleoplasm (approved), Vesicles (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA002977	PC-3	Nucleoplasm
			Vesicles
			Plasma membrane

GENE INFORMATION
Gene name	MTMR1
Synonyms
Description	Myotubularin related protein 1 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the myotubularin related family of proteins. Members of this family contain the consensus sequence for the active site of protein tyrosine phosphatases. Alternatively spliced variants have been described but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	X
Cytoband	q28
Chromosome location (bp)	150692971 - 150765103
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000063601 (version 83.38)
Entrez gene	8776
UniProt	Q13613 (UniProt - Evidence at protein level)
neXtProt	NX_Q13613
Antibodypedia	MTMR1 antibodies

PROTEIN BROWSER

MTMR1-002	MTMR1-005	MTMR1-006	MTMR1-007	MTMR1-008	MTMR1-009	MTMR1-010	MTMR1-012	MTMR1-013	MTMR1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MTMR1-002 ENSP00000414178 ENST00000445323	F8WA39 [Direct mapping] Myotubularin-related protein 1 Show all	Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0004725 [protein tyrosine phosphatase activity] GO:0005737 [cytoplasm] GO:0005886 [plasma membrane] GO:0016311 [dephosphorylation] GO:0016791 [phosphatase activity] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	673 aa 75.7 kDa	No	0
MTMR1-005 ENSP00000390736 ENST00000429965	F8W764 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	87 aa 9.6 kDa	No	0
MTMR1-006 ENSP00000389884 ENST00000438018	H7BZJ1 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	132 aa 14.8 kDa	No	0
MTMR1-007 ENSP00000414925 ENST00000436701	H7C406 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	149 aa 16.8 kDa	No	0
MTMR1-008 ENSP00000436957 ENST00000490316	E9PPP8 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	185 aa 19.5 kDa	No	0
MTMR1-009 ENSP00000404599 ENST00000439546	F8W8S8 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	90 aa 10 kDa	No	0
MTMR1-010 ENSP00000405946 ENST00000434699	F8W764 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	87 aa 9.6 kDa	No	0
MTMR1-012 ENSP00000431992 ENST00000493995	E9PIH9 [Direct mapping] Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	147 aa 16.7 kDa	No	0
MTMR1-013 ENSP00000359417 ENST00000370390	Q13613 [Direct mapping] Myotubularin-related protein 1 Show all	Enzymes ENZYME proteins Hydrolases Phobius predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0004725 [protein tyrosine phosphatase activity] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0005886 [plasma membrane] GO:0006644 [phospholipid metabolic process] GO:0006661 [phosphatidylinositol biosynthetic process] GO:0016311 [dephosphorylation] GO:0016791 [phosphatase activity] GO:0035335 [peptidyl-tyrosine dephosphorylation] GO:0044281 [small molecule metabolic process] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	665 aa 74.7 kDa	No	0
MTMR1-201 ENSP00000445281 ENST00000542156	Q8NEC6 [Direct mapping] MTMR1 protein; Myotubularin related protein 1, isoform CRA_b; Myotubularin-related protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0004438 [phosphatidylinositol-3-phosphatase activity] GO:0046856 [phosphatidylinositol dephosphorylation] GO:0052629 [phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity] Show all	363 aa 39.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.