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In atlas

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Detectable

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ROPN1
  • TISSUE

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TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation


Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

ROPN1

Gene description

Rhophilin associated tail protein 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

10
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic expression in testis.

DATA RELIABILITY

Data reliability
description

Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded. Pending external verification.

Reliability score

Approved based on 2 antibodies.
HPA052530 , CAB014875
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
Cerebral cortex
Hippocampus
N/A
Caudate
N/A
Cerebellum
N/A
Endocrine tissues
Thyroid gland
Parathyroid gland
Adrenal gland
Bone marrow & immune system
Appendix
Bone marrow
Lymph node
Tonsil
Spleen
Muscle tissues
Heart muscle
Skeletal muscle
Smooth muscle
Lung
Nasopharynx
N/A
Bronchus
N/A
Lung
Liver & gallbladder
Liver
Gallbladder
Pancreas
Pancreas
Gastrointestinal tract
Oral mucosa
N/A
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Colon
Rectum
Kidney & urinary bladder
Kidney
Urinary bladder
Male tissues
Testis
Epididymis
Prostate
Seminal vesicle
Female tissues
Breast
Vagina
N/A
Cervix, uterine
Endometrium
Fallopian tube
Ovary
Placenta
Adipose & soft tissue
Adipose tissue
Soft tissue
N/A
Skin
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW

Organ
Expression
Alphabetical
Cerebral cortexHippocampusCaudateCerebellumThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleNasopharynxBronchusLungLiverGallbladderPancreasOral mucosaSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSoft tissueSkinNotdetectedLowMediumHighSCORE

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
Cerebral cortexThyroid glandParathyroid glandAdrenal glandAppendixBone marrowLymph nodeTonsilSpleenHeart muscleSkeletal muscleSmooth muscleLungLiverGallbladderPancreasSalivary glandEsophagusStomachDuodenumSmall intestineColonRectumKidneyUrinary bladderTestisEpididymisProstateSeminal vesicleBreastCervix, uterineEndometriumFallopian tubeOvaryPlacentaAdipose tissueSkin050100150200250TPM
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
HypothalamusPituitary glandCerebral cortexHippocampusCaudateCerebellumThyroid glandAdrenal glandSpleenHeart muscleSkeletal muscleLungLiverPancreasSalivary glandEsophagusStomachSmall intestineColonKidneyUrinary bladderTestisProstateBreastVaginaCervix, uterineEndometriumFallopian tubeOvaryAdipose tissueSkin01020304050RPKM

GENE INFORMATION

Gene name

ROPN1 (HGNC Symbol)

Synonyms

CT91, ODF6, ROPN1A, ropporin

Description

Rhophilin associated tail protein 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is found in the fibrous sheath of spermatazoa, where it interacts with rhophilin, a Rho GTPase binding protein. The encoded protein also can bind an A-kinase anchoring protein (AKAP110) and a calcium-binding tyrosine phosphorylation-regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer-testis antigen in hematologic malignancies. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015]

Chromosome

3

Cytoband

q21.1

Chromosome location (bp)

123968521 - 123992178

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065371 (version 83.38)

Entrez gene

54763

UniProt

Q9HAT0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HAT0

Antibodypedia

ROPN1 antibodies

PROTEIN BROWSER

ROPN1-001
ROPN1-002
ROPN1-003
ROPN1-004
ROPN1-005
ROPN1-008
ROPN1-009
ROPN1-010
ROPN1-013
ROPN1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ROPN1-001
ENSP00000184183
ENST00000184183
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
212 aa
23.9 kDa
No 0
ROPN1-002
ENSP00000420567
ENST00000479867
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
58 aa
6.7 kDa
No 0
ROPN1-003
ENSP00000417379
ENST00000495093
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
58 aa
6.7 kDa
No 0
ROPN1-004
ENSP00000420590
ENST00000459660
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
58 aa
6.7 kDa
No 0
ROPN1-005
ENSP00000385919
ENST00000405845
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
212 aa
23.9 kDa
No 0
ROPN1-008
ENSP00000418931
ENST00000496145
C9J012 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
77 aa
8.8 kDa
No 0
ROPN1-009
ENSP00000420310
ENST00000460743
C9JP07 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
116 aa
13.2 kDa
No 0
ROPN1-010
ENSP00000419205
ENST00000484329
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
58 aa
6.7 kDa
No 0
ROPN1-013
ENSP00000417067
ENST00000467907
C9J6H4 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
130 aa
14.8 kDa
No 0
ROPN1-201
ENSP00000483603
ENST00000620893
Q9HAT0 [Direct mapping]
Ropporin-1A
Show all
Predicted intracellular proteins
Show all
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005737 [cytoplasm]
GO:0007264 [small GTPase mediated signal transduction]
Show all
212 aa
23.9 kDa
No 0

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