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PDCD7

GENERAL INFORMATION

Gene name

 PDCD7

Gene description

 Programmed cell death 7

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Granular cytoplasmic expression in several tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification. Sub cellular location is contradicted by external data.

Reliability score

 Approved based on 1 antibody.
HPA049388
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 PDCD7 (HGNC Symbol)

Synonyms

 ES18, HES18

Description

 Programmed cell death 7 (HGNC Symbol)

Entrez gene summary

 This gene encodes a 59 kDa protein that is associated with the U11 small nuclear ribonucleoprotein (snRNP), which is a component of the minor U12-type spliceosome responsible for catalyzing pre-mRNA splicing of U12-type introns. [provided by RefSeq, Dec 2010]

Chromosome

 15

Cytoband

 q22.31

Chromosome location (bp)

 65117379 - 65133836

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000090470 (version 83.38)

Entrez gene

 10081

UniProt

 Q8N8D1 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8N8D1

Antibodypedia

 PDCD7 antibodies

PROTEIN BROWSER
PDCD7-001
PDCD7-005

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PDCD7-001
ENSP00000204549
ENST00000204549
Q8N8D1 [Direct mapping]
Programmed cell death protein 7
Q6IEG3 [Target identity:100%; Query identity:100%]
Programmed cell death 7, isoform CRA_a; U11/U12 snRNP 59K
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000398 [mRNA splicing, via spliceosome]
GO:0005654 [nucleoplasm]
GO:0005689 [U12-type spliceosomal complex]
GO:0006915 [apoptotic process]
GO:0008380 [RNA splicing]
GO:0010467 [gene expression]
GO:0051384 [response to glucocorticoid]
GO:0070234 [positive regulation of T cell apoptotic process]
GO:2001235 [positive regulation of apoptotic signaling pathway]
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 485 aa
54.7 kDa 		No 0
PDCD7-005
ENSP00000457053
ENST00000560313
H3BT73 [Direct mapping]
Programmed cell death protein 7
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 103 aa
12 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.