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Term
Gene name

Class

Subclass

Chromosome

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In atlas

Reliability

Reliability

Reliability

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Method

Validation

Method

Validation

Method

Validation

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Searches

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Specificity

Cell line

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Cancer

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Detectable

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Detectable

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BTAF1
  • TISSUE

  • CELL

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TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

BTAF1

Gene description

BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

BTAF1 (HGNC Symbol)

Synonyms

MOT1, TAF(II)170, TAF-172, TAF172, TAFII170

Description

BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (HGNC Symbol)

Entrez gene summary

This gene encodes a TAF (TATA box-binding protein-associated factor), which associates with TBP (TATA box-binding protein) to form the B-TFIID complex that is required for transcription initiation of genes by RNA polymerase II. This TAF has DNA-dependent ATPase activity, which drives the dissociation of TBP from DNA, freeing the TBP to associate with other TATA boxes or TATA-less promoters. [provided by RefSeq, Sep 2011]

Chromosome

10

Cytoband

q23.32

Chromosome location (bp)

91923769 - 92030325

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000095564 (version 83.38)

Entrez gene

9044

UniProt

O14981 (UniProt - Evidence at protein level)

neXtProt

NX_O14981

Antibodypedia

BTAF1 antibodies

PROTEIN BROWSER

BTAF1-001
BTAF1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BTAF1-001
ENSP00000265990
ENST00000265990
O14981 [Direct mapping]
TATA-binding protein-associated factor 172
Q2M1V9 [Target identity:100%; Query identity:100%]
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae), isoform CRA_a
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0004386 [helicase activity]
GO:0005488 [binding]
GO:0005524 [ATP binding]
GO:0005634 [nucleus]
GO:0008152 [metabolic process]
GO:0035562 [negative regulation of chromatin binding]
GO:0045892 [negative regulation of transcription, DNA-templated]
Show all
1849 aa
206.9 kDa
No 0
BTAF1-201
ENSP00000439924
ENST00000544642
A0A0A0MTH9 [Direct mapping]
TATA-binding protein-associated factor 172
Show all
   MEMSAT3 predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005488 [binding]
GO:0005524 [ATP binding]
Show all
1849 aa
206.9 kDa
No 0

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The Human Protein Atlas project is funded
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