Fields »
ABOUT
HELP
BLOG
PAGE4

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 PAGE4

Gene description

 P antigen family, member 4 (prostate associated)

Protein class

 Cancer-related genes
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Mainly localized to vesicles. In addition localized to the Golgi apparatus.

RNA cell category

 Group enriched (U-266/84, U-266/70, CACO-2)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Vesicles (approved)

Additional location

 In addition localized to the Golgi apparatus (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA023880
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Group enriched (U-266/84, U-266/70, CACO-2)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Mainly localized to vesicles. In addition localized to the Golgi apparatus.

Main location

 Vesicles (approved)

Additional location

 Golgi apparatus (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA023880 CACO-2 Vesicles
HPA023880 U-2 OS Golgi apparatus
Vesicles
HPA023880 U-251 MG Golgi apparatus
Vesicles

GENE INFORMATION

Gene name

 PAGE4 (HGNC Symbol)

Synonyms

 CT16.7, GAGEC1, PAGE-4

Description

 P antigen family, member 4 (prostate associated) (HGNC Symbol)

Entrez gene summary

 This gene is a member of the GAGE family. The GAGE genes are expressed in a variety of tumors and in some fetal and reproductive tissues. This gene is strongly expressed in prostate and prostate cancer. It is also expressed in other male and female reproductive tissues including testis, fallopian tube, uterus, and placenta, as well as in testicular cancer and uterine cancer. The protein encoded by this gene shares sequence similarity with other GAGE/PAGE proteins, and also belongs to a family of CT (cancer-testis) antigens. The protein may play a role in benign and malignant prostate diseases. A related pseudogene is located on chromosome 7. [provided by RefSeq, Aug 2013]

Chromosome

 X

Cytoband

 p11.23

Chromosome location (bp)

 49829260 - 49833973

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000101951 (version 83.38)

Entrez gene

 9506

UniProt

 O60829 (UniProt - Evidence at transcript level)

neXtProt

 NX_O60829

Antibodypedia

 PAGE4 antibodies

PROTEIN BROWSER
PAGE4-001
PAGE4-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
PAGE4-001
ENSP00000218068
ENST00000218068
O60829 [Direct mapping]
P antigen family member 4
Show all
Predicted intracellular proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
 102 aa
11.2 kDa 		No 0
PAGE4-004
ENSP00000365311
ENST00000376141
O60829 [Direct mapping]
P antigen family member 4
Show all
Predicted intracellular proteins
Cancer-related genes
   Candidate cancer biomarkers
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0005575 [cellular_component]
GO:0008150 [biological_process]
Show all
 102 aa
11.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.