Expression of JADE3 in cancer - Summary - The Human Protein Atlas

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JADE3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	JADE3
Gene description	Jade family PHD finger 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (BEWO)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA006007
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA006007

GENE INFORMATION
Gene name	JADE3 (HGNC Symbol)
Synonyms	JADE-3, KIAA0215, PHF16
Description	Jade family PHD finger 3 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
Chromosome	X
Cytoband	p11.3
Chromosome location (bp)	46912276 - 47061242
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000102221 (version 83.38)
Entrez gene	9767
UniProt	Q92613 (UniProt - Evidence at protein level)
neXtProt	NX_Q92613
Antibodypedia	JADE3 antibodies

PROTEIN BROWSER

JADE3-001	JADE3-002	JADE3-003	JADE3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
JADE3-001 ENSP00000481850 ENST00000614628	Q92613 [Direct mapping] Protein Jade-3 A0A024R1A2 [Target identity:100%; Query identity:100%] PHD finger protein 16, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000123 [histone acetyltransferase complex] GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0043981 [histone H4-K5 acetylation] GO:0043982 [histone H4-K8 acetylation] GO:0043983 [histone H4-K12 acetylation] Show all	823 aa 93.8 kDa	No	0
JADE3-002 ENSP00000391009 ENST00000424392	F2Z3N8 [Direct mapping] Protein Jade-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		186 aa 21.4 kDa	No	0
JADE3-003 ENSP00000400584 ENST00000455411	F2Z2B6 [Direct mapping] Protein Jade-3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		114 aa 13.2 kDa	No	0
JADE3-201 ENSP00000479377 ENST00000611250	Q92613 [Direct mapping] Protein Jade-3 A0A024R1A2 [Target identity:100%; Query identity:100%] PHD finger protein 16, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000123 [histone acetyltransferase complex] GO:0005515 [protein binding] GO:0008270 [zinc ion binding] GO:0043966 [histone H3 acetylation] GO:0043981 [histone H4-K5 acetylation] GO:0043982 [histone H4-K8 acetylation] GO:0043983 [histone H4-K12 acetylation] Show all	823 aa 93.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.