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AIMP2

GENERAL INFORMATION

Gene name

 AIMP2

Gene description

 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in most tissues.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA019098 , HPA020057
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 AIMP2 (HGNC Symbol)

Synonyms

 JTV-1, JTV1, p38, PRO0992

Description

 Aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 (HGNC Symbol)

Entrez gene summary

 The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown. [provided by RefSeq, Jul 2008]

Chromosome

 7

Cytoband

 p22.1

Chromosome location (bp)

 6009245 - 6023834

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000106305 (version 83.38)

Entrez gene

 7965

UniProt

 Q13155 (UniProt - Evidence at protein level)

neXtProt

 NX_Q13155

Antibodypedia

 AIMP2 antibodies

PROTEIN BROWSER
AIMP2-001
AIMP2-003
AIMP2-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AIMP2-001
ENSP00000223029
ENST00000223029
Q13155 [Direct mapping]
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
A0A024QZY1 [Target identity:100%; Query identity:100%]
JTV1 gene, isoform CRA_a
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0006418 [tRNA aminoacylation for protein translation]
GO:0006915 [apoptotic process]
GO:0008285 [negative regulation of cell proliferation]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0031398 [positive regulation of protein ubiquitination]
GO:0060510 [Type II pneumocyte differentiation]
GO:1901216 [positive regulation of neuron death]
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 320 aa
35.3 kDa 		No 0
AIMP2-003
ENSP00000383327
ENST00000400479
A8MU58 [Direct mapping]
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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 242 aa
26.8 kDa 		No 0
AIMP2-004
ENSP00000378658
ENST00000395236
F8W950 [Direct mapping]
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 251 aa
27.8 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.