Tissue expression of RAPGEFL1 - Summary

GENERAL INFORMATION
Gene name	RAPGEFL1
Gene description	Rap guanine nucleotide exchange factor (GEF)-like 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enhanced (skin)
GTEx:	Expressed in all
FANTOM5:	Mixed

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enhanced (skin)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Mixed

GENE INFORMATION
Gene name	RAPGEFL1 (HGNC Symbol)
Synonyms	Link-GEFII
Description	Rap guanine nucleotide exchange factor (GEF)-like 1 (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q21.1
Chromosome location (bp)	40177010 - 40195656
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108352 (version 83.38)
Entrez gene	51195
UniProt	Q9UHV5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UHV5
Antibodypedia	RAPGEFL1 antibodies

PROTEIN BROWSER

RAPGEFL1-001	RAPGEFL1-004	RAPGEFL1-005	RAPGEFL1-006	RAPGEFL1-007	RAPGEFL1-008	RAPGEFL1-011	RAPGEFL1-012	RAPGEFL1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RAPGEFL1-001 ENSP00000484772 ENST00000613811	A0A087X280 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	459 aa 49.8 kDa	No	0
RAPGEFL1-004 ENSP00000438631 ENST00000544503	F5H2D5 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	505 aa 58 kDa	No	0
RAPGEFL1-005 ENSP00000394530 ENST00000456989	Q9UHV5 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Phobius predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005622 [intracellular] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007264 [small GTPase mediated signal transduction] GO:0007399 [nervous system development] GO:0016020 [membrane] GO:0043547 [positive regulation of GTPase activity] Show all	511 aa 58.8 kDa	No	0
RAPGEFL1-006 ENSP00000440006 ENST00000538884	F5GY17 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		20 aa 2.2 kDa	No	0
RAPGEFL1-007 ENSP00000264644 ENST00000264644	Q9UHV5 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005622 [intracellular] GO:0007186 [G-protein coupled receptor signaling pathway] GO:0007264 [small GTPase mediated signal transduction] GO:0007399 [nervous system development] GO:0016020 [membrane] GO:0043547 [positive regulation of GTPase activity] Show all	456 aa 52.3 kDa	No	0
RAPGEFL1-008 ENSP00000441059 ENST00000538981	F5GXC6 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		101 aa 11.8 kDa	No	0
RAPGEFL1-011 ENSP00000440226 ENST00000543876	F5GYJ3 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005057 [receptor signaling protein activity] GO:0005622 [intracellular] GO:0007165 [signal transduction] GO:0035556 [intracellular signal transduction] Show all	149 aa 17.2 kDa	No	0
RAPGEFL1-012 ENSP00000444646 ENST00000541245	F5H582 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		62 aa 7.1 kDa	No	0
RAPGEFL1-201 ENSP00000479735 ENST00000620260	A0A087WVW6 [Direct mapping] Rap guanine nucleotide exchange factor-like 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005085 [guanyl-nucleotide exchange factor activity] GO:0005622 [intracellular] GO:0007264 [small GTPase mediated signal transduction] GO:0043547 [positive regulation of GTPase activity] Show all	662 aa 73.3 kDa	No	0