Tissue expression of FAF2 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	FAF2
Gene description	Fas associated factor family member 2
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	FAF2 (HGNC Symbol)
Synonyms	ETEA, KIAA0887, UBXD8, UBXN3B
Description	Fas associated factor family member 2 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
Chromosome	5
Cytoband	q35.2
Chromosome location (bp)	176447628 - 176510074
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000113194 (version 83.38)
Entrez gene	23197
UniProt	Q96CS3 (UniProt - Evidence at protein level)
neXtProt	NX_Q96CS3
Antibodypedia	FAF2 antibodies

PROTEIN BROWSER

FAF2-001	FAF2-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
FAF2-001 ENSP00000261942 ENST00000261942	Q96CS3 [Direct mapping] FAS-associated factor 2 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005783 [endoplasmic reticulum] GO:0005811 [lipid particle] GO:0006986 [response to unfolded protein] GO:0030433 [ER-associated ubiquitin-dependent protein catabolic process] GO:0030970 [retrograde protein transport, ER to cytosol] GO:0031625 [ubiquitin protein ligase binding] GO:0034098 [VCP-NPL4-UFD1 AAA ATPase complex] GO:0034389 [lipid particle organization] GO:0035473 [lipase binding] GO:0043086 [negative regulation of catalytic activity] GO:0043130 [ubiquitin binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0055102 [lipase inhibitor activity] Show all	445 aa 52.6 kDa	No	1
FAF2-003 ENSP00000424146 ENST00000510730	D6RBG6 [Direct mapping] FAS-associated factor 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		48 aa 5.5 kDa	No	0