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TCERG1

GENERAL INFORMATION

Gene name

 TCERG1

Gene description

 Transcription elongation regulator 1

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 General nuclear expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA064854
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 TCERG1 (HGNC Symbol)

Synonyms

 CA150, TAF2S, Urn1

Description

 Transcription elongation regulator 1 (HGNC Symbol)

Entrez gene summary

 This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

 5

Cytoband

 q32

Chromosome location (bp)

 146447311 - 146511961

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000113649 (version 83.38)

Entrez gene

 10915

UniProt

 O14776 (UniProt - Evidence at protein level)

neXtProt

 NX_O14776

Antibodypedia

 TCERG1 antibodies

PROTEIN BROWSER
TCERG1-001
TCERG1-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TCERG1-001
ENSP00000296702
ENST00000296702
O14776 [Direct mapping]
Transcription elongation regulator 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001103 [RNA polymerase II repressing transcription factor binding]
GO:0001106 [RNA polymerase II transcription corepressor activity]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0015629 [actin cytoskeleton]
GO:0044822 [poly(A) RNA binding]
GO:0070064 [proline-rich region binding]
Show all
 1098 aa
123.9 kDa 		No 0
TCERG1-007
ENSP00000377943
ENST00000394421
O14776 [Direct mapping]
Transcription elongation regulator 1
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription from RNA polymerase II promoter]
GO:0001103 [RNA polymerase II repressing transcription factor binding]
GO:0001106 [RNA polymerase II transcription corepressor activity]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0015629 [actin cytoskeleton]
GO:0044822 [poly(A) RNA binding]
Show all
 1077 aa
121.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.