Cell atlas - AADAC - The Human Protein Atlas

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AADAC

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION

GENE/PROTEIN

Dictionary

Human cell

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GENERAL INFORMATION
Gene name	AADAC
Gene description	Arylacetamide deacetylase
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION
Summary
RNA cell category	Cell line enhanced (A549, EFO-21)
Protein evidence	Evidence at protein level
Main location	Not available

DATA RELIABILITY
Reliability score	Pending cell analysis.

ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (A549, EFO-21) Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

GENE INFORMATION
Gene name	AADAC (HGNC Symbol)
Synonyms	CES5A1, DAC
Description	Arylacetamide deacetylase (HGNC Symbol)
Entrez gene summary	Microsomal arylacetamide deacetylase competes against the activity of cytosolic arylamine N-acetyltransferase, which catalyzes one of the initial biotransformation pathways for arylamine and heterocyclic amine carcinogens [provided by RefSeq, Jul 2008]
Chromosome	3
Cytoband	q25.1
Chromosome location (bp)	151814037 - 151828488
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000114771 (version 83.38)
Entrez gene	13
UniProt	P22760 (UniProt - Evidence at protein level)
neXtProt	NX_P22760
Antibodypedia	AADAC antibodies

PROTEIN BROWSER

AADAC-001	AADAC-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AADAC-001 ENSP00000232892 ENST00000232892	P22760 [Direct mapping] Arylacetamide deacetylase Show all	Enzymes ENZYME proteins Hydrolases MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003824 [catalytic activity] GO:0004806 [triglyceride lipase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006805 [xenobiotic metabolic process] GO:0008152 [metabolic process] GO:0010898 [positive regulation of triglyceride catabolic process] GO:0016021 [integral component of membrane] GO:0016298 [lipase activity] GO:0016787 [hydrolase activity] GO:0017171 [serine hydrolase activity] GO:0019213 [deacetylase activity] GO:0044281 [small molecule metabolic process] GO:0052689 [carboxylic ester hydrolase activity] Show all	399 aa 45.7 kDa	No	0
AADAC-002 ENSP00000419620 ENST00000488869	C9K0E9 [Direct mapping] Arylacetamide deacetylase Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008152 [metabolic process] GO:0016021 [integral component of membrane] GO:0016787 [hydrolase activity] Show all	204 aa 23.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.