Expression of PRICKLE4 in cancer - Summary - The Human Protein Atlas

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PRICKLE4

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	PRICKLE4
Gene description	Prickle homolog 4
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Cell line enhanced (AF22, ASC TERT1, HeLa, TIME)
HPA (normal tissue):	Mixed

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and lung cancer (favourable).
Renal cancer p<0.001 Lung cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	PRICKLE4 (HGNC Symbol)
Synonyms	C6orf49, DKFZp761H221, OEBT
Description	Prickle homolog 4 (HGNC Symbol)
Entrez gene summary	C6ORF49 is a member of the LIM domain protein family (Teufel et al., 2005 [PubMed 15702247]).[supplied by OMIM, Mar 2008]
Chromosome	6
Cytoband	p21.1
Chromosome location (bp)	41780349 - 41790141
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000124593 (version 83.38)
Entrez gene	29964
UniProt	Q2TBC4 (UniProt - Evidence at transcript level)
neXtProt	NX_Q2TBC4
Antibodypedia	PRICKLE4 antibodies

PROTEIN BROWSER

PRICKLE4-201	PRICKLE4-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PRICKLE4-201 ENSP00000352128 ENST00000359201	Q2TBC4 [Direct mapping] Prickle-like protein 4 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] Show all	344 aa 37.6 kDa	No	0
PRICKLE4-202 ENSP00000404911 ENST00000458694	Q2TBC4 [Direct mapping] Prickle-like protein 4 Show all	Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0005634 [nucleus] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] Show all	384 aa 41.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.