Cell atlas - RIOK1 - The Human Protein Atlas

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RIOK1

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TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Cytosol
	Nuclear speckles
	Nucleoli

Human cell
	Cytosol
	Nucleoli
	Nucleoplasm

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GENERAL INFORMATION
Gene name	RIOK1
Gene description	RIO kinase 1
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Mainly localized to the nucleoli & nuclear speckles. In addition localized to the cytosol.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoli (approved), Nuclear speckles (approved)
Additional location	In addition localized to the Cytosol (approved)

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA051446
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Mainly localized to the nucleoli & nuclear speckles. In addition localized to the cytosol.

Main location

Nucleoli (approved), Nuclear speckles (approved)

Additional location

Cytosol (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA051446	HeLa	Nuclear speckles
	HPA051446	HeLa	Cytosol
	HPA051446	PC-3	Nucleoli
			Nuclear speckles
			Cytosol
	HPA051446	U-2 OS	Nuclear speckles

GENE INFORMATION
Gene name	RIOK1 (HGNC Symbol)
Synonyms	AD034, bA288G3.1, FLJ30006, RRP10
Description	RIO kinase 1 (HGNC Symbol)
Entrez gene summary	This gene includes two alternatively spliced transcript variants, which encode different isoforms. The function of this gene has not been determined. [provided by RefSeq, Jul 2008]
Chromosome	6
Cytoband	p24.3
Chromosome location (bp)	7389496 - 7418037
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000124784 (version 83.38)
Entrez gene	83732
UniProt	Q9BRS2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BRS2
Antibodypedia	RIOK1 antibodies

PROTEIN BROWSER

RIOK1-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
RIOK1-001 ENSP00000369162 ENST00000379834	Q9BRS2 [Direct mapping] Serine/threonine-protein kinase RIO1 Show all	Enzymes ENZYME proteins Transferases Kinases Atypical kinases Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0006468 [protein phosphorylation] Show all	568 aa 65.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.