Cell atlas - STK35 - The Human Protein Atlas

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STK35

TISSUE

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CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nuclear bodies
	Nucleus

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	STK35
Gene description	Serine/threonine kinase 35
Protein class	Enzymes Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleus & nuclear bodies.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleus (supported), Nuclear bodies (approved)

DATA RELIABILITY
Reliability score	Supported based on 1 antibody. HPA026452
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleus & nuclear bodies.

Main location

Nucleus (supported), Nuclear bodies (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA026452	HaCaT	Nucleus
	HPA026452	HaCaT	Nuclear bodies
	HPA026452	Hep G2	No staining
	HPA026452	U-2 OS	Nucleus
	HPA026452	U-2 OS	Nuclear bodies

GENE INFORMATION
Gene name	STK35 (HGNC Symbol)
Synonyms	bA550O8.2, CLIK1
Description	Serine/threonine kinase 35 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008]
Chromosome	20
Cytoband	p13
Chromosome location (bp)	2101611 - 2177038
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000125834 (version 83.38)
Entrez gene	140901
UniProt	Q8TDR2 (UniProt - Evidence at protein level)
neXtProt	NX_Q8TDR2
Antibodypedia	STK35 antibodies

PROTEIN BROWSER

STK35-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
STK35-001 ENSP00000370891 ENST00000381482	Q8TDR2 [Direct mapping] Serine/threonine-protein kinase 35 Show all	Enzymes ENZYME proteins Transferases Kinases MEMSAT-SVM predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0004672 [protein kinase activity] GO:0004674 [protein serine/threonine kinase activity] GO:0005524 [ATP binding] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006468 [protein phosphorylation] Show all	534 aa 58.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.