Tissue expression of CSN1S1 - Summary - The Human Protein Atlas

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CSN1S1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	CSN1S1
Gene description	Casein alpha s1
Protein class	Cancer-related genes Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Tissue enriched (breast)
GTEx:	Group enriched (adipose tissue, breast)
FANTOM5:	Group enriched (adipose tissue, breast)

Protein evidence

Evidence at protein level

Protein expression

Cytoplasmic and membranous expression with additional plasma positivity in lactating breast.

DATA RELIABILITY
Data reliability description	No internal RNA expression data available for correlation. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Supported based on 2 antibodies. HPA035659 , HPA057031
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Lactating breast

N/A

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Lactating breast

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Tissue enriched (breast)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, breast)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (adipose tissue, breast)

GENE INFORMATION
Gene name	CSN1S1 (HGNC Symbol)
Synonyms	CASA, CSN1
Description	Casein alpha s1 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	69931081 - 69946574
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000126545 (version 83.38)
Entrez gene	1446
UniProt	P47710 (UniProt - Evidence at protein level)
neXtProt	NX_P47710
Antibodypedia	CSN1S1 antibodies

PROTEIN BROWSER

CSN1S1-001	CSN1S1-002	CSN1S1-003	CSN1S1-004	CSN1S1-005	CSN1S1-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CSN1S1-001 ENSP00000246891 ENST00000246891	P47710 [Direct mapping] Alpha-S1-casein Casoxin-D Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Show all	GO:0005215 [transporter activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0055085 [transmembrane transport] Show all	185 aa 21.7 kDa	Yes	0
CSN1S1-002 ENSP00000427490 ENST00000507772	E9PDQ1 [Direct mapping] Alpha-S1-casein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005215 [transporter activity] GO:0005576 [extracellular region] GO:0006810 [transport] Show all	177 aa 20.8 kDa	Yes	0
CSN1S1-003 ENSP00000422611 ENST00000507763	P47710 [Direct mapping] Alpha-S1-casein Casoxin-D Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Cancer-related genes Candidate cancer biomarkers Show all	GO:0005215 [transporter activity] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0055085 [transmembrane transport] Show all	176 aa 20.7 kDa	Yes	0
CSN1S1-004 ENSP00000421314 ENST00000510936	H0Y8K1 [Direct mapping] Alpha-S1-casein Show all	Predicted intracellular proteins Show all	GO:0005215 [transporter activity] GO:0005576 [extracellular region] GO:0006810 [transport] Show all	76 aa 9 kDa	No	0
CSN1S1-005 ENSP00000426684 ENST00000505782	D6RF34 [Direct mapping] Alpha-S1-casein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005215 [transporter activity] GO:0005576 [extracellular region] GO:0006810 [transport] Show all	169 aa 19.9 kDa	Yes	0
CSN1S1-006 ENSP00000487633 ENST00000633258		Predicted intracellular proteins Show all		55 aa 6.4 kDa	No	0

Contact

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.