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A majority of cancer tissues displayed moderate, often granular, cytoplasmic staining combined with membranous positivity. Colorectal, breast and endometrial cancers were strongly stained in a majority of cases. Testicular cancers were weakly stained or negative.
GENE INFORMATION
Gene name
BST2 (HGNC Symbol)
Synonyms
CD317, tetherin
Description
Bone marrow stromal cell antigen 2 (HGNC Symbol)
Entrez gene summary
Bone marrow stromal cells are involved in the growth and development of B-cells. The specific function of the protein encoded by the bone marrow stromal cell antigen 2 is undetermined; however, this protein may play a role in pre-B-cell growth and in rheumatoid arthritis. [provided by RefSeq, Jul 2008]