Cell atlas - GRSF1 - The Human Protein Atlas

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GRSF1

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Mitochondria

Human cell
	Mitochondria

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GENERAL INFORMATION
Gene name	GRSF1
Gene description	G-rich RNA sequence binding factor 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the mitochondria.
RNA cell category	Expressed in all
Protein evidence	Evidence at protein level
Main location	Localized to the Mitochondria (validated)

DATA RELIABILITY
Reliability score	Validated based on 2 antibodies. HPA036984 , HPA036985
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ASSAYS

RNA expression

Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Expressed in all Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the mitochondria.

Main location

Mitochondria (validated)


	Toggle channels	Low High G1 S G2 M N/A

Antibody	Cell line	Location
HPA036984	A-431	Mitochondria
HPA036984	U-2 OS	Mitochondria
HPA036984	U-251 MG	Mitochondria
HPA036985	A-431	Mitochondria
HPA036985	U-2 OS	Mitochondria
HPA036985	U-251 MG	Mitochondria

GENE INFORMATION
Gene name	GRSF1
Synonyms
Description	G-rich RNA sequence binding factor 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	70815782 - 70839945
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132463 (version 83.38)
Entrez gene	2926
UniProt	Q12849 (UniProt - Evidence at protein level)
neXtProt	NX_Q12849
Antibodypedia	GRSF1 antibodies

PROTEIN BROWSER

GRSF1-001	GRSF1-004	GRSF1-005	GRSF1-006	GRSF1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRSF1-001 ENSP00000254799 ENST00000254799	Q12849 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006378 [mRNA polyadenylation] GO:0008033 [tRNA processing] GO:0009952 [anterior/posterior pattern specification] GO:0016331 [morphogenesis of embryonic epithelium] GO:0035770 [ribonucleoprotein granule] GO:0042645 [mitochondrial nucleoid] GO:0044822 [poly(A) RNA binding] Show all	480 aa 53.1 kDa	No	0
GRSF1-004 ENSP00000427354 ENST00000499044	H0YAK1 [Direct mapping] G-rich sequence factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0005739 [mitochondrion] Show all	453 aa 51 kDa	No	0
GRSF1-005 ENSP00000421789 ENST00000514161	H0Y8R1 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	417 aa 47.3 kDa	No	0
GRSF1-006 ENSP00000425430 ENST00000502323	Q12849 [Direct mapping] G-rich sequence factor 1 A0A024RD99 [Target identity:100%; Query identity:100%] G-rich RNA sequence binding factor 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006378 [mRNA polyadenylation] GO:0008033 [tRNA processing] GO:0035770 [ribonucleoprotein granule] GO:0042645 [mitochondrial nucleoid] GO:0044822 [poly(A) RNA binding] Show all	318 aa 36.6 kDa	No	0
GRSF1-201 ENSP00000443380 ENST00000545193	F5H5I6 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0005739 [mitochondrion] Show all	424 aa 48 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.