Tissue expression of GRSF1 - Summary - The Human Protein Atlas

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GRSF1

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GRSF1
Gene description	G-rich RNA sequence binding factor 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression with a granular pattern.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Supported based on 2 antibodies. HPA036984 , HPA036985
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	GRSF1
Synonyms
Description	G-rich RNA sequence binding factor 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a cellular protein that binds RNAs containing the G-rich element. The protein is localized in the cytoplasm, and has been shown to stimulate translation of viral mRNAs in vitro. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q13.3
Chromosome location (bp)	70815782 - 70839945
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000132463 (version 83.38)
Entrez gene	2926
UniProt	Q12849 (UniProt - Evidence at protein level)
neXtProt	NX_Q12849
Antibodypedia	GRSF1 antibodies

PROTEIN BROWSER

GRSF1-001	GRSF1-004	GRSF1-005	GRSF1-006	GRSF1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GRSF1-001 ENSP00000254799 ENST00000254799	Q12849 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006378 [mRNA polyadenylation] GO:0008033 [tRNA processing] GO:0009952 [anterior/posterior pattern specification] GO:0016331 [morphogenesis of embryonic epithelium] GO:0035770 [ribonucleoprotein granule] GO:0042645 [mitochondrial nucleoid] GO:0044822 [poly(A) RNA binding] Show all	480 aa 53.1 kDa	No	0
GRSF1-004 ENSP00000427354 ENST00000499044	H0YAK1 [Direct mapping] G-rich sequence factor 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0005739 [mitochondrion] Show all	453 aa 51 kDa	No	0
GRSF1-005 ENSP00000421789 ENST00000514161	H0Y8R1 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] Show all	417 aa 47.3 kDa	No	0
GRSF1-006 ENSP00000425430 ENST00000502323	Q12849 [Direct mapping] G-rich sequence factor 1 A0A024RD99 [Target identity:100%; Query identity:100%] G-rich RNA sequence binding factor 1, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003729 [mRNA binding] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0006378 [mRNA polyadenylation] GO:0008033 [tRNA processing] GO:0035770 [ribonucleoprotein granule] GO:0042645 [mitochondrial nucleoid] GO:0044822 [poly(A) RNA binding] Show all	318 aa 36.6 kDa	No	0
GRSF1-201 ENSP00000443380 ENST00000545193	F5H5I6 [Direct mapping] G-rich sequence factor 1 Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0005739 [mitochondrion] Show all	424 aa 48 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.